Meyenberger C
Departement für Innere Medizin, Universitätsspital Zürich.
Schweiz Rundsch Med Prax. 1993 Apr 20;82(16):475-80.
Irritable bowel syndrome is a very common clinical problem with a broad spectrum of severity. The management includes a combination of positive diagnosis of typical symptoms with limited investigations to exclude underlying structural or biochemical disorders. Therapeutic trials focus on the relief of predominant symptoms. Identification and modification of factors exacerbating symptoms, behavioural techniques and pharmacologic agents directed to the presumed gastrointestinal motor dysfunction are required. Psychological support by the physician is the most important part of treatment. Chronic constipation may be the predominant symptom of irritable bowel syndrome. Underlying organic disorders must be excluded by clinical examination and endoscopy. Severe chronic constipation requires further investigation of colonic motility and defecation. High fibre diet, osmotic laxatives and procinetic agents may lead to an improvement. In rare cases surgery may be indicated.
肠易激综合征是一种非常常见的临床问题,严重程度范围广泛。其管理包括通过有限的检查对典型症状进行阳性诊断,以排除潜在的结构或生化紊乱。治疗试验侧重于缓解主要症状。需要识别和改变加重症状的因素、行为技术以及针对假定的胃肠运动功能障碍的药物。医生给予的心理支持是治疗的最重要部分。慢性便秘可能是肠易激综合征的主要症状。必须通过临床检查和内镜检查排除潜在的器质性疾病。严重的慢性便秘需要进一步检查结肠动力和排便情况。高纤维饮食、渗透性泻药和促动力剂可能会有所改善。在极少数情况下可能需要手术治疗。