Cardiology Division, Internal Medicine Department, Santos Reyes Hospital, Avenida Ruperta Baraya S/N, Aranda de Duero, Burgos, Spain.
Clinical Cardiology Unit, Cardiology Department, Burgos University Hospital, Burgos, Spain.
Sleep Breath. 2023 Dec;27(6):2181-2189. doi: 10.1007/s11325-023-02789-1. Epub 2023 Mar 27.
Obstructive sleep apnoea (OSA) and cardiac conduction disorders are pathologies with a rising prevalence due to increased life expectancy. Upper airway patency is affected by environmental factors that may be associated with seasonal periods. The ability to record the degree of nocturnal apnoea on a daily basis may provide a more accurate picture of seasonal variability.
This study used an observational, cross-sectional design recruiting consecutive patients with Sorin/Livanova/Microport® pacemakers. The study assessed the seasonal influence on the daily degree of nocturnal apnoea over a minimum period of 180 days. The respiratory events were recorded using a pacemaker-integrated detection algorithm based on transthoracic impedance variation. A generalised linear repeated measure mixed model was used to study the seasonal effect.
A sample of 101 subjects with a mean of 227 valid nights was compiled. Summer was associated with higher RDI (respiratory disturbance index) values and winter with lower values. The mean daily RDI ratio in summer was 1.099 times higher than in winter.
Slight seasonal influences on the degree of nocturnal apnoea were detected through the daily observation of an unselected sample of pacemaker wearers. The degree of apnoea is higher in warmer months and lower in colder months.
阻塞性睡眠呼吸暂停（OSA）和心脏传导障碍是由于预期寿命延长而患病率上升的两种疾病。上呼吸道通畅受环境因素影响，这些因素可能与季节性有关。记录夜间呼吸暂停程度的能力可能提供更准确的季节性变化情况。
本研究采用观察性、横断面设计，连续招募 Sorin/Livanova/Microport®起搏器患者。研究评估了至少 180 天的季节性对夜间呼吸暂停每日程度的影响。使用基于经胸阻抗变化的起搏器集成检测算法记录呼吸事件。使用广义线性重复测量混合模型研究季节性效应。
编制了 101 名受试者的样本，平均有 227 个有效夜晚。夏季 RDI（呼吸紊乱指数）值较高，冬季较低。夏季的平均每日 RDI 比值比冬季高 1.099 倍。
通过对起搏器佩戴者未选择样本的日常观察，检测到夜间呼吸暂停程度存在轻微的季节性影响。在温暖的月份呼吸暂停程度较高，在寒冷的月份较低。
