在瑞典，1960 年至 2014 年间子宫内膜癌的发病率上升且存活率提高：一项基于人群的登记调查。
Increased incidence and improved survival in endometrial cancer in Sweden 1960-2014: a population-based registry survey.
机构信息
Department of Obstetrics and Gynecology, Skåne University Hospital Lund, Lund University, Klinikgatan 12, 221 85, Lund, Sweden.
Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
出版信息
BMC Cancer. 2023 Mar 27;23(1):276. doi: 10.1186/s12885-023-10746-0.
BACKGROUND
An investigation of trends of incidence and net survival (NS) for endometrial cancer in Sweden.
METHODS
Morphologically verified endometrial carcinoma diagnosed 1960 to 2014 were collected from the nation-wide Swedish Cancer Registry. Endometrial cancer patients were assessed with regards to time trends for incidence and 54,825 cases remained for survival analyses. Cases diagnosed 1995 to 2014 were categorized according to detailed morphology and from 2005 to 2014 FIGO stage was also categorized.
RESULTS
There was a trend of increasing incidence of endometrial carcinoma for women above 55 years of age. NS was improved at 5- and 10-year follow-up. The 5-year net survival in 2010-2014 was 86%. The most prominent improvement in NS was found in the elderly women above 75 years of age.
CONCLUSIONS
This study observed increased incidence of endometrial cancer in Sweden from 1960 to 2014. The progress in diagnostics and treatment, seem to have improved the net survival, especially in elderly women.
背景
对瑞典子宫内膜癌发病率和净生存率（NS）趋势的调查。
方法
从全国性的瑞典癌症登记处收集了 1960 年至 2014 年间经形态学验证的子宫内膜癌诊断病例。对子宫内膜癌患者的发病率进行了时间趋势评估，54825 例患者仍可进行生存分析。1995 年至 2014 年诊断的病例根据详细的形态学进行分类，2005 年至 2014 年FIGO 分期也进行了分类。
结果
55 岁以上女性的子宫内膜癌发病率呈上升趋势。5 年和 10 年随访的 NS 有所改善。2010-2014 年的 5 年净生存率为 86%。在 75 岁以上的老年女性中，NS 的改善最为显著。
结论
本研究观察到 1960 年至 2014 年瑞典子宫内膜癌发病率的增加。诊断和治疗的进展似乎改善了净生存率，特别是在老年女性中。
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