Betty and Guy Beatty Center for Integrated Research, Inova Health System, Falls Church, VA, USA.
Department of Global and Community Health, George Mason University, Fairfax, VA, USA.
Ann Med. 2023 Dec;55(1):1345-1353. doi: 10.1080/07853890.2023.2193422.
Fine motor performance may serve as an early warning sign for reduced cognitive function. Physical activity can help preserve cognitive function; however, the relationship between fine motor performance and physical activity is not well understood. Therefore, this study examined the relationship between fine motor performance and physical activity in individuals at risk for developing cognitive impairment (those with diabetes and/or non-alcoholic fatty liver disease (NAFLD)).
Individuals aged 25-69 with and without diabetes and NAFLD were enrolled. For this cross-sectional study, all participants completed the Human Activity Profile and fine motor performance tasks (Grooved Pegboard Test and Trail Making Test).
There were 93 participants in the study (NAFLD only ( = 29); diabetes + NAFLD ( = 34), controls ( = 30)). Individuals with both diabetes and NAFLD were less physically active and performed slower on the fine motor performance task. A statistically significant correlation was found between physical activity and motor speed among those with NAFLD only ( = 0.436, <.05), which remained statistically significant after controlling for body mass index ( = 0.385; <.05).
This study suggests that those with diabetes + NAFLD have lower levels of physical activity and slower fine motor performance. The relationship between physical activity and fine motor performance was only statistically significant in the group of individuals with NAFLD only. Future research needs to explore the mechanisms that impact fine motor performance and physical activity in individuals at risk for mild cognitive impairment. Individuals with diabetes and/or NAFLD should be identified, advised and encouraged to engage in physical activity.Key MessagesThose with NAFLD and T2DM have lower levels of physical activity and slower fine motor performance compared to controls and those with NAFLD only.Future research needs to explore the mechanisms that impact fine motor performance and physical activity in those with T2DM with or without NAFLD.Individuals with impaired fine motor performance should be identified and encouraged to engage in physical activity.
精细运动表现可能是认知功能下降的早期预警信号。身体活动有助于保持认知功能；然而，精细运动表现与身体活动之间的关系尚不清楚。因此，本研究检查了有发生认知障碍风险的个体（即患有糖尿病和/或非酒精性脂肪性肝病 (NAFLD) 的个体）的精细运动表现与身体活动之间的关系。
招募了年龄在 25-69 岁之间的患有和不患有糖尿病和 NAFLD 的个体。在这项横断面研究中，所有参与者都完成了人类活动概况和精细运动表现任务（槽钉板测试和连线测试）。
该研究共有 93 名参与者（仅 NAFLD（ = 29）；糖尿病 + NAFLD（ = 34），对照组（ = 30））。同时患有糖尿病和 NAFLD 的个体身体活动较少，精细运动表现较慢。仅患有 NAFLD 的个体中，身体活动与运动速度之间存在显著的相关性（ = 0.436，<0.05），在控制体重指数后仍然具有统计学意义（ = 0.385；<0.05）。
本研究表明，患有糖尿病 + NAFLD 的个体身体活动水平较低，精细运动表现较慢。仅患有 NAFLD 的个体中，身体活动与精细运动表现之间仅存在统计学上的显著相关性。未来的研究需要探讨影响有轻度认知障碍风险的个体的精细运动表现和身体活动的机制。应识别、建议和鼓励患有糖尿病和/或 NAFLD 的个体进行身体活动。
与对照组和仅患有 NAFLD 的个体相比，患有 NAFLD 和 T2DM 的个体身体活动水平较低，精细运动表现较慢。未来的研究需要探讨影响 T2DM 合并或不合并 NAFLD 个体精细运动表现和身体活动的机制。应识别和鼓励精细运动表现受损的个体进行身体活动。
