Belova T I, Petrova N V, Jonsson G
Biull Eksp Biol Med. 1986 Apr;101(4):395-7.
To study the role of locus ceruleus in maintaining the blood-brain barrier function in conditions of emotional stress, the blood-brain barrier permeability was estimated after locus ceruleus damaging with DSP4 (N-2-chloroethyl-N-ethyl-2-bromobenzylamine). The importance of locus ceruleus for the integrity of blood-brain barrier functions in control animals and especially in rats exposed to emotional stress was revealed. The data obtained prove the homeostatic role of locus ceruleus, which is the most prominent in conditions of emotional stress.
为研究蓝斑在情绪应激状态下维持血脑屏障功能中的作用，在用DSP4（N-2-氯乙基-N-乙基-2-溴苄胺）损毁蓝斑后评估血脑屏障通透性。揭示了蓝斑对正常动物尤其是遭受情绪应激的大鼠血脑屏障功能完整性的重要性。所获数据证明了蓝斑的稳态作用，这在情绪应激状态下最为显著。
