Belova T I
Biull Eksp Biol Med. 1989 Jul;108(7):101-5.
Emotional stress in rats resulted in blood-brain barrier increased permeability and brain parenchymal vessel disruptions. Stress induced microvascular damages were mainly observed in midbrain reticular formation. In this article the components of midbrain reticular formation were studied 1, 2, 4 and 6 weeks after immobilization stress. The destructive changes in some neurons, glia cells and myelin fibers were shown up to 6 weeks after immobilization. The signs of the recovery were also observed. It was supposed that the brain parenchymal vessel damages under emotional stress were due to the stress induced locus coeruleus dysfunctions.
大鼠的情绪应激导致血脑屏障通透性增加和脑实质血管破坏。应激诱导的微血管损伤主要见于中脑网状结构。在本文中，研究了制动应激后1、2、4和6周中脑网状结构的组成部分。在制动后6周内，一些神经元、胶质细胞和髓鞘纤维出现了破坏性变化。也观察到了恢复的迹象。据推测，情绪应激下脑实质血管损伤是由于应激诱导的蓝斑功能障碍所致。
