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[辐射对分离的肝线粒体大小的影响]

[Effect of irradiation on the size of isolated liver mitochondria].

作者信息

Avtandilov G G, Sirotkin V V, Dovzhenko Iu M, Lobzin A P

出版信息

Biull Eksp Biol Med. 1986 Apr;101(4):409-11.

PMID:3697486
Abstract

The role of external effects in the time course of changes in hepatocyte mitochondria size was studied. Suspensions of mitochondria isolated from the liver of inbred mice were investigated at various periods after gamma irradiation. Statistical analysis of changes in the size of isolated mitochondria has shown that irradiation leads to an increase in mitochondria size, reflected in the distribution pattern. The changes may be related to the functional activity, and distribution shifts may be regarded as manifestations of hepatocyte adaptation.

摘要

研究了外部效应在肝细胞线粒体大小变化时间进程中的作用。在γ射线照射后的不同时间段,对从近交系小鼠肝脏中分离出的线粒体悬浮液进行了研究。对分离出线粒体大小变化的统计分析表明,照射会导致线粒体大小增加,这反映在分布模式上。这些变化可能与功能活性有关,分布变化可被视为肝细胞适应性的表现。

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