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[辐射对分离的肝线粒体大小的影响]

[Effect of irradiation on the size of isolated liver mitochondria].

作者信息

Avtandilov G G, Sirotkin V V, Dovzhenko Iu M, Lobzin A P

出版信息

Biull Eksp Biol Med. 1986 Apr;101(4):409-11.

PMID:3697486
Abstract

The role of external effects in the time course of changes in hepatocyte mitochondria size was studied. Suspensions of mitochondria isolated from the liver of inbred mice were investigated at various periods after gamma irradiation. Statistical analysis of changes in the size of isolated mitochondria has shown that irradiation leads to an increase in mitochondria size, reflected in the distribution pattern. The changes may be related to the functional activity, and distribution shifts may be regarded as manifestations of hepatocyte adaptation.

摘要

研究了外部效应在肝细胞线粒体大小变化时间进程中的作用。在γ射线照射后的不同时间段,对从近交系小鼠肝脏中分离出的线粒体悬浮液进行了研究。对分离出线粒体大小变化的统计分析表明,照射会导致线粒体大小增加,这反映在分布模式上。这些变化可能与功能活性有关,分布变化可被视为肝细胞适应性的表现。

相似文献

1
[Effect of irradiation on the size of isolated liver mitochondria].[辐射对分离的肝线粒体大小的影响]
Biull Eksp Biol Med. 1986 Apr;101(4):409-11.
2
[Morphofunctional characteristics of mouse liver mitochondria (morphologic and biochemical study)].
Biull Eksp Biol Med. 1981 Aug;92(8):96-7.
3
[A mathematical model of the processes of mitochondrial death and reproduction during body irradiation].[身体辐射过程中线粒体死亡与增殖过程的数学模型]
Biull Eksp Biol Med. 1990 Mar;109(3):257-9.
4
[Effect of radiomodifiers on lipid peroxidation and the structural-functional state of irradiated mitochondria].[辐射修饰剂对脂质过氧化及受照线粒体结构功能状态的影响]
Radiobiologiia. 1987 Mar-Apr;27(2):242-5.
5
[Three-factor correlation analysis of morphofunctional changes in mitochondria based on the results of morphologic and biochemical studies].基于形态学和生化研究结果的线粒体形态功能变化的三因素相关性分析
Biull Eksp Biol Med. 1993 Mar;115(3):303-5.
6
[Lipids from liver microsomes and mitochondria upon acute and chronic gamma-irradiation of rats].
Biokhimiia. 1994 Jul;59(7):1027-33.
7
[Inhibition of phospholipase activity in liver mitochondria of gamma-irradiated rats].[γ射线照射大鼠肝脏线粒体中磷脂酶活性的抑制作用]
Radiobiologiia. 1985 Jul-Aug;25(4):551-3.
8
The effect of gamma irradiation on the rat liver, intestine and heart muscle mitochondria.γ射线辐照对大鼠肝脏、肠道和心肌线粒体的影响。
Folia Histochem Cytochem (Krakow). 1981;19(2):79-85.
9
[Prostaglandin synthetase activity in the liver, brain and testicles of F1 (CBA X C57B1) mice under gamma irradiation].[γ射线照射下F1(CBA×C57B1)小鼠肝脏、脑和睾丸中前列腺素合成酶活性]
Radiobiologiia. 1981 Mar-Apr;21(2):265-9.
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[Effect of Fe2+- and gamma-induced lipid peroxidation on respiration and oxidative phosphorylation in the mitochondria].[亚铁离子和γ射线诱导的脂质过氧化对线粒体呼吸及氧化磷酸化的影响]
Radiobiologiia. 1984 Jan-Feb;24(1):81-3.