Semeniuk A V, Voronin A Iu, Kulikov V Iu, Maianskiĭ D N
Biull Eksp Biol Med. 1986 Apr;101(4):453-5.
The content of malonyl dialdehyde, one of the final products of lipid peroxidation, was determined at different stages after zymosan stimulation of mononuclear phagocyte system in the rat liver. The gradual increase (with the maximum on day 7) of colloidal carbon clearance from the blood and the number of nonparenchymal cells, especially their nonphagocytic fraction, was noted in the rat liver after zymosan injection. A considerable reduction of hepatic malonyl dialdehyde was observed after the initial (on day 1) rising of its level. The distinct antioxidant effect developed by day 7 and coincided with maximal activity of hepatic macrophages.
在大鼠肝脏中，对经酵母聚糖刺激单核吞噬细胞系统后的不同阶段，测定了脂质过氧化终产物之一丙二醛的含量。注射酵母聚糖后，大鼠肝脏中血液胶体碳清除率和非实质细胞数量逐渐增加（第7天达到最大值），尤其是其非吞噬部分。在丙二醛水平最初升高（第1天）后，观察到肝脏丙二醛含量显著降低。到第7天产生了明显的抗氧化作用，且与肝脏巨噬细胞的最大活性相一致。
