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测定溶液中分子水合作用的变化对磁各向异性的影响。

Determination of molecular hydration in solution changes in magnetic anisotropy.

机构信息

Department of Chemistry, The University of Manchester, Manchester, M13 9PL, UK.

Department of Chemistry, Durham University, Durham, DH1 3LE, UK.

出版信息

Chem Commun (Camb). 2023 Apr 11;59(30):4531-4534. doi: 10.1039/d3cc00601h.

DOI:10.1039/d3cc00601h
PMID:36975615
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10088811/
Abstract

The hydration behaviour of coordination complexes is important for understanding their roles as bio-imaging agents. Determination of hydration is difficult, and various optical and NMR-based techniques have been used. Here we use EPR spectroscopy to unambiguously demonstrate that a -butyl-pyridyl-functionalised Er DOTA derivative coordinates water, while its methylphosphinate analogue does not.

摘要

配合物的水合行为对于理解它们作为生物成像剂的作用非常重要。水合的测定很困难，已经使用了各种基于光学和 NMR 的技术。在这里，我们使用 EPR 光谱学明确地证明了 -丁基-吡啶基功能化的 Er DOTA 衍生物与水配位，而其甲基膦酸盐类似物则不与水配位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0a/10088811/3f28871582ff/d3cc00601h-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0a/10088811/67466fff6664/d3cc00601h-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0a/10088811/67cbb4708f1a/d3cc00601h-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0a/10088811/b26c7fe66583/d3cc00601h-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0a/10088811/3f28871582ff/d3cc00601h-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0a/10088811/67466fff6664/d3cc00601h-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0a/10088811/67cbb4708f1a/d3cc00601h-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0a/10088811/b26c7fe66583/d3cc00601h-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0a/10088811/3f28871582ff/d3cc00601h-f4.jpg

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本文引用的文献

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Nat Commun. 2022 Feb 11;13(1):825. doi: 10.1038/s41467-022-28352-2.
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How the Ligand Field in Lanthanide Coordination Complexes Determines Magnetic Susceptibility Anisotropy, Paramagnetic NMR Shift, and Relaxation Behavior.镧系配合物中的配体场如何决定磁各向异性、顺磁 NMR 位移和弛豫行为。
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OpenMolcas：从源代码到洞见。
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Paramagnetic NMR in solution and the solid state.溶液和固态中的顺磁 NMR。
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Sensitivity of Magnetic Anisotropy in the Solid State for Lanthanide Complexes with Small Crystal Field Splitting.具有小晶体场分裂的镧系配合物在固态下的磁各向异性敏感性。
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Electronic Energy Levels of Dysprosium(III) ions in Solution. Assigning the Emitting State and the Intraconfigurational 4f-4f Transitions in the Vis-NIR Region and Photophysical Characterization of Dy(III) in Water, Methanol, and Dimethyl Sulfoxide.溶液中镝（III）离子的电子能级。确定发射态以及在可见-近红外区域内的组态内4f-4f跃迁，并对水中、甲醇中和二甲亚砜中的Dy（III）进行光物理表征。
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Slow Magnetic Relaxation in Lanthanoid Crown Ether Complexes: Interplay of Raman and Anomalous Phonon Bottleneck Processes.镧系冠醚配合物中的缓慢磁弛豫：拉曼和反常声子瓶颈过程的相互作用。
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