Bavaresco Gambassi Bruno, Gonçalves E Silva Daniela Conceição Gomes, Sá Camila Almeida, Bezerra Roberto Rodrigues, de Freitas Cleilson Barbosa, Costa Marcelo Silva, Marques Paulo Roberto da Silva, da Silva Pedro Paulo Ramos, Guimarães Manoel Pereira, Almeida Fabiano de Jesus Furtado, Leite Richard Diego, Sobral Filho Dário Celestino, Schwingel Paulo Adriano
Laboratório de Pesquisas em Desempenho Humano (LAPEDH), Universidade de Pernambuco (UPE), Petrolina 56328-900, PE, Brazil.
Programa de Pós-Graduação em Gestão de Programas e Serviços de Saúde (PPGGPSS), CEUMA, São Luís 65075-120, MA, Brazil.
J Cardiovasc Dev Dis. 2023 Mar 8;10(3):113. doi: 10.3390/jcdd10030113.
Although there are studies on blood pressure (BP) and autonomic cardiac control (ACC) impairments caused by ergogenic aids, research has scarcely addressed this analysis during sleep. This study analyzed BP and ACC during sleep and wake periods in three groups of resistance training (RT) practitioners: ergogenic aid non-users, thermogenic supplement (TS) self-users, and anabolic-androgenic steroid (AAS) self-users.
RT practitioners were selected for the Control Group (CG; = 15), TS self-users Group (TSG; = 15), and AAS self-users Group (AASG; = 15). All individuals underwent cardiovascular Holter monitoring (BP, ACC) during sleep and wake periods.
The maximum systolic BP (SBP) during sleep was higher in AASG ( < 0.01) than CG ( < 0.001). CG had lower mean diastolic BP (DBP) than TSG ( < 0.01) and lower mean SBP ( = 0.009) than the other groups. Additionally, CG had higher values ( < 0.01) than TSG and AASG for SDNN and pNN50 during sleep. HF, LF, and LF/HF ratio values during sleep were statistically different in CG ( < 0.001) from the other groups.
Our findings demonstrate that high doses of TS and AAS can impair cardiovascular parameters during sleep in RT practitioners who take ergogenic aids.
尽管有关于促力补剂导致血压(BP)和自主心脏控制(ACC)受损的研究,但在睡眠期间进行此项分析的研究却很少。本研究分析了三组抗阻训练(RT)从业者在睡眠和清醒期间的血压和自主心脏控制情况:未使用促力补剂者、自行使用产热补充剂(TS)者和自行使用合成代谢雄激素类固醇(AAS)者。
选择RT从业者分为对照组(CG;n = 15)、自行使用TS组(TSG;n = 15)和自行使用AAS组(AASG;n = 15)。所有个体在睡眠和清醒期间均接受心血管动态心电图监测(血压、自主心脏控制)。
AASG睡眠期间的最高收缩压(SBP)高于CG(P < 0.(此处原文有误,推测为<0.01))(P < 0.001)。CG的平均舒张压(DBP)低于TSG(P < 0.01),平均SBP低于其他组(P = 0.009)。此外,CG睡眠期间的SDNN和pNN50值高于TSG和AASG(P < 0.01)。CG睡眠期间的高频(HF)、低频(LF)和LF/HF比值与其他组在统计学上有差异(P < 0.001)。
我们的研究结果表明,高剂量的TS和AAS会损害服用促力补剂的RT从业者睡眠期间的心血管参数。