Tibana Ramires A, Boullosa Daniel A, Leicht Anthony S, Prestes Jonato
Graduation Program on Physical Education, Catholic University of Brasilia, Brasilia, Brazil.
Clin Physiol Funct Imaging. 2013 Sep;33(5):364-72. doi: 10.1111/cpf.12038. Epub 2013 Apr 2.
Metabolic syndrome (MetS) is a cluster of risk factors in individuals with high risk of diabetes and heart disease. Resistance training (RT) has been proposed to be a safe, effective and worthwhile method for the prevention and treatment of metabolic and cardiovascular diseases. However, no study has analysed the acute response of blood pressure (BP) and autonomic control of heart rate (HR) after a RT session in female patients with MetS. The aim of the present study was to analyse the response of laboratory assessed and ambulatory BP and cardiac autonomic modulation after a RT session in women with MetS. Nine women without MetS (35.0 ± 6.7 years) and 10 women with MetS (34.1 ± 9.4 years) completed one experimental exercise session and a control session. Laboratory BP, heart rate variability (HRV) and ambulatory BP of each subject were measured at rest, over 60 min, and for 24 h after the end of the sessions, respectively. There was a significant reduction in systolic blood pressure (SBP), night time diastolic blood pressure (DBP) and mean blood pressure (MBP) only for women with MetS, for all periods after the RT session when compared with the control session (P<0.05). Significantly lower laboratory values of SBP and DBP (10, 30 and 40 min postexercise) and MBP (10, 40 and 50 min postexercise) were observed in women with MetS (P<0.05). Patients with MetS exhibited significant lower basal HRV and a lower autonomic responsiveness during the 60 min of acute recovery. These results confirmed that an acute session of resistance exercise induced a lower BP during day time and sleeping hours in women with MetS that may offer a cardio-protective effect. Women with MetS exhibited an impaired autonomic modulation at rest and a lower acute autonomic responsiveness to a RT session. The dissociation between BP and HRV responses suggests that other factors than autonomic control could be involved in the hypotensive effect of a RT session in MetS patients.
代谢综合征（MetS）是一组存在糖尿病和心脏病高风险个体的危险因素。抗阻训练（RT）已被认为是预防和治疗代谢性疾病及心血管疾病的一种安全、有效且值得采用的方法。然而，尚无研究分析过患有代谢综合征的女性患者在进行一次抗阻训练后血压（BP）的急性反应以及心率（HR）的自主控制情况。本研究的目的是分析患有代谢综合征的女性在进行一次抗阻训练后实验室评估血压和动态血压以及心脏自主神经调节的反应。9名无代谢综合征的女性（35.0±6.7岁）和10名患有代谢综合征的女性（34.1±9.4岁）完成了一次实验性训练课程和一次对照课程。分别在训练结束后静息状态下、60分钟内以及24小时内测量了每个受试者的实验室血压、心率变异性（HRV）和动态血压。与对照课程相比，仅患有代谢综合征的女性在抗阻训练后的所有时间段内，收缩压（SBP）、夜间舒张压（DBP）和平均血压（MBP）均有显著降低（P<0.05）。在患有代谢综合征的女性中观察到，运动后10分钟、30分钟和40分钟的SBP和DBP以及运动后10分钟、40分钟和50分钟的MBP的实验室值显著更低（P<0.05）。患有代谢综合征的患者在急性恢复的60分钟内表现出显著更低的基础HRV和更低的自主反应性。这些结果证实，一次急性抗阻训练会使患有代谢综合征的女性在白天和睡眠时间血压降低，这可能具有心脏保护作用。患有代谢综合征的女性在静息时表现出自主神经调节受损，并且对一次抗阻训练的急性自主反应性较低。血压和HRV反应之间的分离表明，除自主控制外，其他因素可能也参与了抗阻训练对代谢综合征患者的降压作用。
