From University of Tennessee, Knoxville, TN.
Université Paris Descartes, Paris, France.
J Pediatr Gastroenterol Nutr. 2023 Jul 1;77(1):7-15. doi: 10.1097/MPG.0000000000003784. Epub 2023 Mar 28.
Faltering growth (FG) is a problem regularly seen by clinicians in infants and young children (<2 years of age). It can occur due to non-disease-related and disease-related causes and is associated with a wide range of adverse outcomes, including shorter-term effects such as impaired immune responses and increased length of hospital stay, and longer-term consequences, including an impact on schooling and cognitive achievements, short stature, and socioeconomic outcomes. It is essential to detect FG, address underlying causes and support catch-up growth where this is indicated. However, anecdotal reports suggest misplaced fear of promoting accelerated (too rapid) growth may deter some clinicians from adequately addressing FG. An invited international group of experts in pediatric nutrition and growth reviewed the available evidence and guidelines on FG resulting from disease-related and non-disease-related effects on nutritional status in healthy term and small for gestational age infants and children up to the age of 2 years in low-, middle-, and high-income countries. Using a modified Delphi process, we developed practical consensus recommendations to provide clarity and practical recommendations for general clinicians on how FG should be defined in different young child populations at risk, how FG should be assessed and managed, and the role of catch-up growth after a period of FG. We also suggested areas where further research is needed to answer remaining questions on this important issue.
生长迟缓是临床医生在婴幼儿(<2 岁)中经常遇到的问题。它可能由非疾病相关和疾病相关的原因引起,并与广泛的不良后果相关,包括短期影响,如免疫反应受损和住院时间延长,以及长期后果,如对学校教育和认知成就、身材矮小和社会经济结果的影响。检测生长迟缓、解决潜在病因并在需要时支持追赶生长至关重要。然而,一些轶事报道表明,对促进加速(过快)生长的担忧可能会阻止一些临床医生充分解决生长迟缓问题。一组受邀的国际儿科营养和生长专家审查了有关疾病相关和非疾病相关因素对健康足月和小于胎龄儿及儿童营养状况的影响的现有证据和指南,年龄在 2 岁以下,包括低收入、中等收入和高收入国家。我们使用改良 Delphi 流程制定了实用的共识建议,为一般临床医生提供了明确的建议和实用的建议,说明如何在不同有风险的幼儿人群中定义生长迟缓,如何评估和管理生长迟缓,以及在生长迟缓期间后追赶生长的作用。我们还建议在这个重要问题上需要进一步研究的领域。