模拟失重期间颅内外灌注转移：一项随机交叉试验的结果
External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial.
作者信息
Boschert Alessa L, Gauger Peter, Bach Anja, Gerlach Darius, Johannes Bernd, Jordan Jens, Li Zhili, Elmenhorst David, Bauer Andreas, Marshall-Goebel Karina, Tank Jens, Zange Jochen, Rittweger Jörn
机构信息
Department of Muscle and Bone Metabolism, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany.
Institute of Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
出版信息
NPJ Microgravity. 2023 Mar 28;9(1):25. doi: 10.1038/s41526-023-00267-2.
The exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels. Our results suggest a shift from the external to the internal system that might play an important role in the pathomechanism of SANS.
迄今为止，太空飞行相关神经眼科综合征（SANS）的确切病理生理学尚未完全阐明。在本研究中，我们评估了急性头低位对颅内和颅外血管平均血流的影响。我们的结果表明，血流从外部系统向内部系统的转变可能在SANS的发病机制中起重要作用。
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