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四环素污染对水生环境的影响及去除策略

The Impact of Tetracycline Pollution on the Aquatic Environment and Removal Strategies.

作者信息

Amangelsin Yernar, Semenova Yuliya, Dadar Maryam, Aljofan Mohamad, Bjørklund Geir

机构信息

Nazarbayev University School of Medicine, Astana 010000, Kazakhstan.

CONEM Iran Microbiology Research Group, Tehran 1316943551, Iran.

出版信息

Antibiotics (Basel). 2023 Feb 23;12(3):440. doi: 10.3390/antibiotics12030440.

Abstract

Antibacterial drugs are among the most commonly used medications in the world. Tetracycline is a widely used antibiotic for human and animal therapy due to its broad-spectrum activity, high effectiveness, and reasonable cost. The indications for treatment with tetracycline include pneumonia, bone and joint infections, infectious disorders of the skin, sexually transmitted and gastrointestinal infections. However, tetracycline has become a serious threat to the environment because of its overuse by humans and veterinarians and weak ability to degrade. Tetracycline is capable of accumulating along the food chain, causing toxicity to the microbial community, encouraging the development and spread of antibiotic resistance, creating threats to drinking and irrigation water, and disrupting microbial flora in the human intestine. It is essential to address the negative impact of tetracycline on the environment, as it causes ecological imbalance. Ineffective wastewater systems are among the main reasons for the increased antibiotic concentrations in aquatic sources. It is possible to degrade tetracycline by breaking it down into small molecules with less harmful or nonhazardous effects. A range of methods for physical, chemical, and biological degradation exists. The review will discuss the negative effects of tetracycline consumption on the aquatic environment and describe available removal methods.

摘要

抗菌药物是世界上最常用的药物之一。四环素因其广谱活性、高效性和合理的成本,是一种广泛用于人类和动物治疗的抗生素。四环素的治疗适应症包括肺炎、骨和关节感染、皮肤感染性疾病、性传播疾病和胃肠道感染。然而,由于人类和兽医的过度使用以及其降解能力较弱,四环素已对环境构成严重威胁。四环素能够沿食物链积累,对微生物群落产生毒性,促使抗生素耐药性的发展和传播,对饮用水和灌溉用水构成威胁,并破坏人类肠道中的微生物菌群。解决四环素对环境的负面影响至关重要,因为它会导致生态失衡。无效的废水处理系统是导致水源中抗生素浓度增加的主要原因之一。通过将四环素分解为危害较小或无害的小分子来降解它是可行的。存在一系列物理、化学和生物降解方法。本综述将讨论四环素消费对水生环境的负面影响,并描述现有的去除方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4e/10044355/02723a21daaa/antibiotics-12-00440-g001.jpg

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