Elangovan Shakthi, Mudgil Poonam
School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.
Antibiotics (Basel). 2023 Feb 27;12(3):474. doi: 10.3390/antibiotics12030474.
Antimicrobial resistance is a huge threat against the public health sphere and is a major cause of global mortality and morbidity. Antibiotic misuse and overuse have led to the development of many resistant bacterial strains. One particular bacterium of concern is methicillin-resistant (MRSA), which is the most common resistant bacteria in humans. Antibiotic development has been unable to keep up with the rapid evolution of antibiotic-resistant organisms, and there is an urgent need to identify alternative agents to combat this problem. The purpose of this systematic review is to explore the literature on the antibacterial properties of essential oil against MRSA. The articles used in this review were obtained through a systematic search of the literature across four databases, with the timeline being between 2002 and 2022. Twenty studies were included in this review, which used various methods to investigate the antibacterial properties of essential oil, alone or in combination with other agents, against MRSA. The findings suggest that essential oil has antibacterial properties against MRSA, which can be enhanced when used in combination with other agents, such as other essential oils and antibiotics.
抗菌耐药性是对公共卫生领域的巨大威胁,是全球死亡率和发病率的主要原因。抗生素的滥用和过度使用导致了许多耐药菌株的产生。一种特别值得关注的细菌是耐甲氧西林金黄色葡萄球菌(MRSA),它是人类中最常见的耐药细菌。抗生素的研发无法跟上抗生素耐药生物的快速进化,迫切需要找到替代药物来解决这个问题。本系统评价的目的是探讨关于精油对MRSA抗菌特性的文献。本评价中使用的文章是通过对四个数据库进行系统的文献检索获得的,时间跨度为2002年至2022年。本评价纳入了20项研究,这些研究使用了各种方法来研究精油单独或与其他药物联合对MRSA的抗菌特性。研究结果表明,精油对MRSA具有抗菌特性,与其他药物(如其他精油和抗生素)联合使用时,抗菌特性会增强。