Spadari Alessandro, Gialletti Rodolfo, Gandini Marco, Valle Emanuela, Cerullo Anna, Cavallini Damiano, Bertoletti Alice, Rinnovati Riccardo, Forni Giulia, Scilimati Nicola, Giusto Gessica
Department of Veterinary Medical Sciences, University of Bologna, 40136 Bologna, Italy.
Veterinary Teaching Hospital, Department of Veterinary Medicine, 06123 Perugia, Italy.
Animals (Basel). 2023 Mar 20;13(6):1107. doi: 10.3390/ani13061107.
The occurrence of colic could be influenced by the characteristics of a population, geographical area, and feeding management. The aim of this study was to report the short-term postoperative complications and survival rates and to identify factors that might affect the outcome of horses that underwent colic surgery in three Italian surgical referral centres. Data of horses subjected to colic surgery in three referral centres (2018-2021) were analysed. Comparisons of the outcomes were performed using a Mann-Whitney or a Chi square test. Areas under the receiver operating characteristic (ROC) curve and multivariable logistic regression analysis were used for parameters that were significant in the previous univariate analysis. The goodness-of-fit of the model was assessed using the Akike information criterion (AIC). Significance was defined as < 0.05, and odds ratios and 95% confidence intervals were calculated as percentages. A total of 451 horses were included. The survival rate was 68.5% of all of the horses that underwent colic surgery and 80% of the horses surviving anaesthesia. Age, BCS, PCV and TPP before and after surgery, amount of reflux, type of disease, type of lesion, duration of surgery, surgeon's experience, and amount of intra- and postoperative fluids administered influenced the probability of short-term survival. The multivariate analysis revealed that PCV at arrival, TPP after surgery, and BCS had the highest predictive power. This is the first multicentre study in Italy. The results of this study may help surgeons to inform owners regarding the prognosis of colic surgery.
绞痛的发生可能受种群特征、地理区域和饲养管理的影响。本研究的目的是报告短期术后并发症和存活率,并确定可能影响在三个意大利外科转诊中心接受绞痛手术马匹预后的因素。分析了三个转诊中心(2018 - 2021年)接受绞痛手术马匹的数据。使用曼 - 惠特尼检验或卡方检验对结果进行比较。对在先前单变量分析中具有显著意义的参数,使用受试者工作特征(ROC)曲线下面积和多变量逻辑回归分析。使用赤池信息准则(AIC)评估模型的拟合优度。显著性定义为<0.05,并将比值比和95%置信区间计算为百分比。总共纳入了451匹马。在所有接受绞痛手术的马匹中,存活率为68.5%,在麻醉后存活的马匹中为80%。年龄、体况评分(BCS)、术前和术后的红细胞压积(PCV)和总蛋白(TPP)、反流量、疾病类型、病变类型、手术持续时间、外科医生的经验以及术中及术后给予的液体量影响短期存活的概率。多变量分析显示,到达时的PCV、术后的TPP和BCS具有最高的预测能力。这是意大利的第一项多中心研究。本研究结果可能有助于外科医生向马主告知绞痛手术的预后情况。