Allan S G, Cornbleet M A, Carmichael J, Arnott S J, Smyth J F
Cancer. 1986 Jun 15;57(12):2419-21. doi: 10.1002/1097-0142(19860615)57:12<2419::aid-cncr2820571228>3.0.co;2-v.
Adult neuroblastoma is an uncommon malignancy. The authors report three additional cases and review the 39 reported cases in the world literature. Presentation in the abdomen is the most common; a high rate of lower limb presentation is also observed. Incidence is equal between sexes with median age of presentation of 34 years. Survival is greatest after surgical intervention (median, 20.5 months) compared with no surgery (median, 12.5 months). Chemotherapy may benefit individual patients but does not have a major impact on survival. Radiotherapy is indicated for localized, inoperable primaries or painful metastases. The survival rates of this group of patients parallels that of childhood neuroblastoma, Stage III-IV.
成人神经母细胞瘤是一种罕见的恶性肿瘤。作者报告了另外3例病例，并回顾了世界文献中报道的39例病例。腹部表现最为常见；下肢表现的发生率也较高。发病率在男女之间相等，中位发病年龄为34岁。与未接受手术（中位生存期12.5个月）相比，手术干预后的生存期最长（中位生存期20.5个月）。化疗可能使个别患者受益，但对生存率没有重大影响。放疗适用于局限性、无法手术的原发肿瘤或疼痛性转移瘤。这组患者的生存率与儿童神经母细胞瘤Ⅲ-Ⅳ期患者的生存率相似。
