Pardo-Medina Javier, Limón M Carmen, Avalos Javier
Departamento de Genética, Facultad de Biología, Universidad de Sevilla, 41012 Sevilla, Spain.
Centro de Biotecnología y Genómica de Plantas, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Universidad Politécnica de Madrid, 28223 Madrid, Spain.
J Fungi (Basel). 2023 Mar 4;9(3):319. doi: 10.3390/jof9030319.
Light is an important modulating signal in fungi. species stand out as research models for their phytopathogenic activity and their complex secondary metabolism. This includes the synthesis of carotenoids, whose induction by light is their best known photoregulated process. In these fungi, light also affects other metabolic pathways and developmental stages, such as the formation of conidia. Photoreceptor proteins are essential elements in signal transduction from light. genomes contain genes for at least ten photoreceptors: four flavoproteins, one photolyase, two cryptochromes, two rhodopsins, and one phytochrome. Mutations in five of these genes provide information about their functions in light regulation, in which the flavoprotein WcoA, belonging to the White Collar (WC) family, plays a predominant role. Global transcriptomic techniques have opened new perspectives for the study of photoreceptor functions and have recently been used in on a WC protein and a cryptochrome from the DASH family. The data showed that the WC protein participates in the transcriptional control of most of the photoregulated genes, as well as of many genes not regulated by light, while the DASH cryptochrome potentially plays a supporting role in the photoinduction of many genes.
光是真菌中一种重要的调节信号。某些物种因其植物致病活性和复杂的次生代谢而成为研究模型。这包括类胡萝卜素的合成，其由光诱导是其最著名的光调节过程。在这些真菌中，光还影响其他代谢途径和发育阶段，如分生孢子的形成。光受体蛋白是光信号转导中的关键元件。（这些真菌的）基因组包含至少十种光受体的基因：四种黄素蛋白、一种光解酶、两种隐花色素、两种视紫红质和一种光敏色素。其中五个基因的突变提供了它们在光调节中功能的信息，其中属于白领（WC）家族的黄素蛋白WcoA起主要作用。全球转录组学技术为光受体功能的研究开辟了新视角，最近已用于对一种WC蛋白和来自DASH家族的一种隐花色素的研究。数据表明，WC蛋白参与了大多数光调节基因以及许多不受光调节基因的转录控制，而DASH隐花色素可能在许多基因的光诱导中起辅助作用。
