Bee Youn-Shen, Tsai Pei-Jhen, Lin Muh-Chiou, Chu Ming-Ying
Department of Ophthalmology, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st RD, Kaohsiung, 81346, Taiwan.
Yuh-Ing Junior College of Health Care and Management, Kaohsiung, Taiwan.
BMC Ophthalmol. 2018 Nov 21;18(1):302. doi: 10.1186/s12886-018-0962-4.
Amblyopia is a main concern in children undergoing frontalis sling surgery for repairing congenital ptosis. This study aimed to evaluate factors related to amblyopia in children undergoing frontalis sling surgery.
IRB-approved retrospective review of children under the age of 12 who received frontalis sling surgery. Preoperative demographic data, strabismus, margin reflex distance 1 (MRD1), lid fissure height, sling type, refraction errors, surgical outcome and amblyopia were evaluated.
This study included 48 eyelid procedures performed in 38 patients. Median age was 4.0 years. Etiology was congenital ptosis in 42 eyes (87.5%) and blepharophimosis in 6 eyes (12.5%). Mersilene mesh was the sling material used in 36 eyes (75%), silicone in 6 eyes (12.5%), and polytetrafluoroethylene (PTFE) in 6 eyes (12.5%). Mean duration of follow-up was 27.8 ± 25.0 months (range, 3 to 128 months). Amblyopia was observed in 17 eyes (35.4%) at the final follow-up. Factors significantly associated with final amblyopia included blepharophimosis (p = 0.017), preoperative MRD1 ≤ - 1.0 mm (p = 0.038), preoperative lid fissure ≤4.5 mm (p = 0.035), preoperative anisometropia (spherical equivalent) (p = 0.011), and postoperative astigmatism (p = 0.026).
Study results suggest that blepharophimosis, preoperative MRD1 ≤ - 1.0 mm, preoperative lid fissure ≤4.5 mm, preoperative anisometropia (spherical equivalent), and postoperative astigmatism are associated with amblyopia after frontalis sling surgery in patients with congenital ptosis.
弱视是先天性上睑下垂患儿行额肌悬吊手术时主要关注的问题。本研究旨在评估先天性上睑下垂患儿行额肌悬吊手术中与弱视相关的因素。
对12岁以下接受额肌悬吊手术的患儿进行经机构审查委员会批准的回顾性研究。评估术前人口统计学数据、斜视、缘-反光点距离1(MRD1)、睑裂高度、吊带类型、屈光不正、手术结果及弱视情况。
本研究纳入了38例患者的48例眼睑手术。中位年龄为4.0岁。病因方面,42眼(87.5%)为先天性上睑下垂,6眼(12.5%)为睑裂狭小综合征。36眼(75%)使用Mersilene网片作为吊带材料,6眼(12.5%)使用硅胶,6眼(12.5%)使用聚四氟乙烯(PTFE)。平均随访时间为27.8±25.0个月(范围3至128个月)。末次随访时,17眼(35.4%)存在弱视。与最终弱视显著相关的因素包括睑裂狭小综合征(p = 0.017)、术前MRD1≤ -1.0 mm(p = 0.038)、术前睑裂≤4.5 mm(p = 0.035)、术前屈光参差(球镜等效度)(p = 0.011)及术后散光(p = 0.026)。
研究结果表明,睑裂狭小综合征、术前MRD1≤ -1.0 mm、术前睑裂≤4.5 mm、术前屈光参差(球镜等效度)及术后散光与先天性上睑下垂患者额肌悬吊手术后的弱视相关。