（L.）Ohashi 精油的化学成分、体外抗氧化活性和乙酰胆碱酯酶抑制活性
Chemical Composition and In Vitro Antioxidant Activity and Anti-Acetylcholinesterase Activity of Essential Oils from (L.) Ohashi.
机构信息
SDU-ANU Joint Science College, Shandong University, Weihai 264209, China.
Marine College, Shandong University, Weihai 264209, China.
出版信息
Molecules. 2023 Mar 17;28(6):2734. doi: 10.3390/molecules28062734.
The present study aimed to determine the chemical compositions of essential oils (EOs) from (L.) Ohashi and evaluate their antioxidant and anti-cholinesterase activity under the comprehensive influence of chemical components. The essential oils were extracted from (L.) Ohashi by hydrodistillation. A total of 58 organic compounds were identified by GC-FID and GC-MS analysis. The major components of (L.) Ohashi EOs were identified as palmitic acid (22.46%), 1-Octen-3-ol (14.07%), Caryophyllene (7.20%), (Z)-18-Octadec-9-enolide (6.04%), and 3-Hexen-1-ol (4.55%). The antioxidant activity of the essential oils was determined by using ABTS assay, DPPH assay, and FRAP assay, with IC values of 2.12 ± 0.05 mg/mL, 4.73 ± 0.91 mg/mL against the ABTS, DPPH, and FRAP value 117.42 ± 8.10 mM/g. The result showed that it had moderate antioxidant activities in the experiment, which why it is likely that it will be used as an antioxidant. At the same time, the EOs also showed moderate anti-acetylcholinesterase activity. This study expands the chemical and biological knowledge of the EOs of .
本研究旨在确定从（L.）Ohashi 中提取的精油（EOs）的化学成分，并在化学成分的综合影响下评估其抗氧化和抗乙酰胆碱酯酶活性。通过水蒸馏法从（L.）Ohashi 中提取精油。通过 GC-FID 和 GC-MS 分析鉴定出 58 种有机化合物。（L.）Ohashi EOs 的主要成分鉴定为棕榈酸（22.46％），1-辛烯-3-醇（14.07％），石竹烯（7.20％），（Z）-18-十八烯-9-烯醇（6.04％）和 3-己烯-1-醇（4.55％）。通过 ABTS 测定法，DPPH 测定法和 FRAP 测定法测定了精油的抗氧化活性，其 IC 值分别为 2.12±0.05mg/mL，4.73±0.91mg/mL 对抗 ABTS，DPPH 和 FRAP 值为 117.42±8.10mM/g。结果表明，在实验中它具有中等的抗氧化活性，因此很可能将其用作抗氧化剂。同时，精油还表现出中等的抗乙酰胆碱酯酶活性。这项研究扩展了精油的化学和生物学知识。
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