Aschermann M, Rasmunssen K, Henningsen P, Thomsen P E, Jezek V, Vancura J
Cor Vasa. 1986;28(1):53-60.
The authors studied at repeated ventriculographic examinations the changes in the left ventricular function after application of routinely used ionic contrast medium and of newer nonionic medium. They demonstrated that ionic medium does not significantly change the left ventricular volume and ejection fraction, but influences the left ventricular diastolic function. Nonionic contrast material does not significantly change the left ventricular function. The mechanism of side-effects of contrast agents and possible indications for the application of nonionic contrast media are discussed.
作者通过反复的心室造影检查，研究了常规使用的离子型造影剂和新型非离子型造影剂应用后左心室功能的变化。他们证明，离子型造影剂不会显著改变左心室容积和射血分数，但会影响左心室舒张功能。非离子型造影剂不会显著改变左心室功能。文中讨论了造影剂副作用的机制以及非离子型造影剂的可能应用指征。
