Xu Bingqing, Yu Longgang, Jiang Yan, Wang Lin, Yan Xudong, Zhang Jisheng
Department of Otorhinolaryngology Head and Neck Surgery and Skull Base Surgery，the AffiliatedHospital of Qingdao University，Qingdao，266000，China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Apr;37(4):247-251. doi: 10.13201/j.issn.2096-7993.2023.04.002.
To investigate the etiological characteristics of nasal bacterial infection in patients with nasal lymphoma. The results of bacterial culture of nasal secretions from 39 healthy people and 86 patients with nasal lymphoma in the Affiliated Hospital of Qingdao University from January 2019 to June 2022 were retrospectively analyzed, and the differences in nasal bacteria distribution between nasal lymphoma and healthy people were analyzed and compared. Corynebacterium（38.90%） was the most common bacteria in the nasal cavity of healthy people, followed by coagulase-negative Staphylococcus（31.95%）, Staphylococcus epidermidis（15.28%） and Staphylococcus aureus（6.95%）. The most common bacteria in nasal lymphoma patients was Staphylococcus aureus（30.37%）, followed by Corynebacterium（9.63%）, Staphylococcus epidermidis（7.41%） and coagulase negative Staphylococcus（6.67%）. A total of 81 nasal lymphoma patients were detected with bacteria, positive rate is as high as 94.19%（81/86）. Staphylococcus aureus is the main pathogenic bacteria in nasal secretion of patients with nasal lymphoma, which provides guiding significance for the clinical prevention and treatment of nasal lymphoma complicated with infection or not.
探讨鼻腔淋巴瘤患者鼻腔细菌感染的病原学特征。回顾性分析2019年1月至2022年6月青岛大学附属医院39例健康人和86例鼻腔淋巴瘤患者鼻腔分泌物细菌培养结果，分析比较鼻腔淋巴瘤与健康人鼻腔细菌分布差异。健康人鼻腔最常见细菌为棒状杆菌（38.90%），其次为凝固酶阴性葡萄球菌（31.95%）、表皮葡萄球菌（15.28%）和金黄色葡萄球菌（6.95%）。鼻腔淋巴瘤患者最常见细菌为金黄色葡萄球菌（30.37%），其次为棒状杆菌（9.63%）、表皮葡萄球菌（7.41%）和凝固酶阴性葡萄球菌（6.67%）。共检测出81例鼻腔淋巴瘤患者有细菌感染，阳性率高达94.19%（81/86）。金黄色葡萄球菌是鼻腔淋巴瘤患者鼻腔分泌物中的主要病原菌，对鼻腔淋巴瘤合并感染与否的临床防治具有指导意义。
