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来自sp. SA61的抗蚜虫聚酮化合物。

Anti-Aphid Polyketides from sp. SA61.

作者信息

Wang Ning, Zhu Kaihui, Bi Yuhui, Liu Fei, Yu Zhiguo

机构信息

College of Plant Protection, Shenyang Agricultural University, Shenyang 110866, People's Republic of China.

出版信息

J Nat Prod. 2023 Apr 28;86(4):791-796. doi: 10.1021/acs.jnatprod.2c00961. Epub 2023 Mar 29.

Abstract

(Sulzer) is a crop pest causing serious economic losses around the world. For many decades, the management of has relied heavily on chemical pesticides, resulting in the development of resistance, and new compounds with activity against are needed. Five novel polyketides, strekingmycins A-E (-), were isolated from sp. SA61. Their structures were determined based on MS, NMR, and X-ray diffraction data. Strekingmycins were active against between 4.4 and 9.4 μg/mL.

摘要

(苏尔泽菌)是一种在全球范围内造成严重经济损失的农作物害虫。几十年来,对其的防治严重依赖化学农药,导致了抗药性的产生,因此需要开发对其有活性的新化合物。从SA61菌株中分离出了五种新型聚酮化合物,链霉菌素A-E(-)。它们的结构是根据质谱、核磁共振和X射线衍射数据确定的。链霉菌素对(苏尔泽菌)的活性在4.4至9.4微克/毫升之间。

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