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治疗药物水平与毒理学筛查。

Therapeutic drug levels and toxicology screen.

作者信息

Epstein F B, Hassan M

出版信息

Emerg Med Clin North Am. 1986 May;4(2):367-76.

PMID:3698892
Abstract

Toxicologic analysis cannot supplant physician skills in the diagnosis and management of poisoning; however, it is a useful adjunct when properly used. Laboratory use should reflect critical consideration of clinical contribution as well as insight into institutional capability. A detailed historic review and interview of multiple sources may provide more useful and expeditious information than the blind "drug screen." Test ordering should be limited to that which directly contributes to clinical patient management.16 Similarly, test results must be interpreted in the clinical context of patient presentation. The reported units of measurement must be carefully scrutinized; and the potential for laboratory error must be appreciated. Most importantly, communication and cooperation must be maintained between the physician and laboratory personnel if the resource is to be optimally used.

摘要

毒理学分析不能替代医生在中毒诊断和处理方面的技能;然而,若使用得当,它是一种有用的辅助手段。实验室检测的应用应体现对临床作用的审慎考量以及对机构能力的洞察。对多个信息源进行详细的病史回顾和询问,可能比盲目进行“药物筛查”提供更有用、更快捷的信息。检测项目应仅限于直接有助于临床患者管理的项目。同样,检测结果必须结合患者临床表现的临床背景进行解读。必须仔细审查报告的测量单位;必须认识到存在实验室误差的可能性。最重要的是,如果要最佳利用这一资源,医生和实验室人员之间必须保持沟通与合作。

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