Department of Pathology and Laboratory Medicine, Lahey Hospital and Medical Center, Burlington, Massachusetts.
Department of Clinical Biology, School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda; Department of Pathology, University Teaching Hospital of Kigali, Kigali, Rwanda.
Mod Pathol. 2023 May;36(5):100168. doi: 10.1016/j.modpat.2023.100168. Epub 2023 Mar 27.
With the advent of increasing emerging infectious diseases, rising antibiotic resistance, and the growing number of immunocompromised patients, there is increasing demand for infectious disease (ID) pathology expertise and microbiology testing. Currently, ID pathology training and emerging molecular microbiology techniques (eg, metagenomic next-generation sequencing and whole genome sequencing) are not included in the most American Council of Graduate Medical Education medical microbiology fellowship curricula, and not surprisingly, many institutions lack anatomical pathologists with expertise in ID pathology and advanced molecular diagnostics. In this article, we describe the curriculum and structure of the Franz von Lichtenberg Fellowship in Infectious Disease and Molecular Microbiology at Brigham and Women's Hospital in Boston, MA. We emphasize the value of a training model that strives to integrate anatomical pathology, clinical pathology, and molecular pathology by providing examples in a case-based format and presenting selected metrics of the potential effect of such integrative ID pathology service and briefly describing opportunities and challenges of our global health efforts in Rwanda.
随着新发传染病的出现、抗生素耐药性的上升以及免疫功能低下患者数量的增加,对传染病(ID)病理学专业知识和微生物学检测的需求不断增加。目前,ID 病理学培训和新兴的分子微生物学技术(例如,宏基因组下一代测序和全基因组测序)并未包含在大多数美国研究生医学教育理事会医学微生物学奖学金课程中,毫不奇怪,许多机构缺乏具有 ID 病理学和高级分子诊断专业知识的解剖病理学家。在本文中,我们描述了马萨诸塞州波士顿布莱根妇女医院弗朗茨·冯·利希滕贝格传染病和分子微生物学奖学金的课程和结构。我们强调了一种培训模式的价值,该模式通过以案例为基础的格式提供示例,并提出此类整合的 ID 病理学服务的潜在效果的选定指标,努力将解剖病理学、临床病理学和分子病理学融为一体,并简要描述了我们在卢旺达开展全球卫生工作的机会和挑战。