Americas Oncologia, RJ, Brazil.
Laboratórios Servier do Brazil, RJ, Brazil.
J Geriatr Oncol. 2023 May;14(4):101477. doi: 10.1016/j.jgo.2023.101477. Epub 2023 Mar 27.
Colorectal cancer is a disease of older patients, but few guidelines directly address age in their recommendations. Older patients may present comorbidities that affect the choice of chemotherapy, and care must be taken when choosing the best approach. This narrative review aimed to describe the literature regarding approved oral agents for third-line treatment in older patients with refractory metastatic colorectal cancer, regorafenib, and trifluridine/tipiracil (FTD/TPI).
结直肠癌是一种老年患者的疾病，但很少有指南在其建议中直接涉及年龄。老年患者可能存在影响化疗选择的合并症，因此在选择最佳治疗方法时必须谨慎。本叙述性综述旨在描述有关批准用于难治性转移性结直肠癌老年患者三线治疗的口服药物，regorafenib 和 trifluridine/tipiracil（FTD/TPI）的文献。
