Jegadeeshwari Anitha, Seelam Narasimha Reddy, Myneni Venkata Ratnam
Department of Chemical Engineering, Rajalakshmi Engineering College, Chennai-602105, India.
Department of Chemical Engineering, Mettu University, Metu, Ethiopia.
Int J Anal Chem. 2023 Mar 20;2023:6352503. doi: 10.1155/2023/6352503. eCollection 2023.
The study showed the ability to synthesize environmentally friendly silver nanoparticles (AgNPs) using extracts from seeds and stems. Surface plasmon resonance peaks in the UV-Vis absorption spectra of both plant extracts verified AgNP synthesis. The structural and morphological properties of the AgNPs were investigated using analytical techniques such as XRD, FTIR, TEM, and EDAX. The AgNPs have an FCC crystalline structure, according to XRD study, and their sizes range from 20 to 40 nm, according to TEM images. Based on the results, these plant extracts have been identified as suitable bioresources for AgNP production. The study also showed that both AgNPs had significant levels of antibacterial activity when tested on four different microbial strains using the agar-well diffusion method. The bacteria tested included two Gram-positive strains ( and ) and two Gram-negative strains ( and ). Furthermore, the AgNPs were found to have a significant anticancer effect on MCF-7 cell lines, suggesting that they may be useful in therapeutic applications. Overall, this research highlights the potential of the plant extracts considered as a source for synthesizing eco-friendly AgNPs with potential applications in medicine and other fields.
该研究表明，利用种子和茎的提取物能够合成环境友好型银纳米颗粒（AgNPs）。两种植物提取物的紫外-可见吸收光谱中的表面等离子体共振峰证实了AgNP的合成。使用XRD、FTIR、TEM和EDAX等分析技术研究了AgNPs的结构和形态特性。根据XRD研究，AgNPs具有面心立方晶体结构，根据TEM图像，其尺寸范围为20至40纳米。基于这些结果，这些植物提取物已被确定为生产AgNP的合适生物资源。该研究还表明，使用琼脂孔扩散法在四种不同的微生物菌株上进行测试时，两种AgNPs均具有显著水平的抗菌活性。测试的细菌包括两种革兰氏阳性菌株（ 和 ）和两种革兰氏阴性菌株（ 和 ）。此外，发现AgNPs对MCF-7细胞系具有显著的抗癌作用，这表明它们可能在治疗应用中有用。总体而言，这项研究突出了植物提取物作为合成具有医学和其他领域潜在应用的环保型AgNPs来源的潜力。
