Baptiste P, Bouvard G, Ahkong M V, Verwaerde J C, Ségol P
Gastroenterol Clin Biol. 1986 Feb;10(2):141-6.
The aim of this study was to compare gastroesophageal 99mTc scintiscanning (GES), the pH reflux test (TRA) and esophageal manometry in the assessment of gastroesophageal reflux (GER). GES was performed after oral intake of sulfur colloid labeled with 99m technetium and 300 ml of water. Calculation of an index of reflux gave a semi-quantitative assessment of the GER. Sixty patients with symptoms of GER (typical in 51 cases, atypical in 9 cases) had the three tests. A GES was also performed in 17 normal volunteers and in 12 patients of the series after fundoplication. The diagnostic specificity of GES was 1.0 in GER. GES was less frequently positive than the pH reflux test in GER (68.6 p. 100 versus 80.4 p. 100) but the difference was not significant. These two tests were more sensitive than manometry. The index of reflux was higher in patients than in control subjects (p less than 0.0005) and returned to normal values after fundoplication. A correlation between the index of reflux and the stage of pH-reflux test was observed. It is suggested that GES can be used in the initial assessment of GER as an alternative to TRA and performed repeatedly during the follow-up of patients treated surgically.
本研究的目的是比较胃食管99mTc闪烁扫描（GES）、pH反流试验（TRA）和食管测压在评估胃食管反流（GER）中的作用。口服用99m锝标记的硫化胶体和300毫升水后进行GES。反流指数的计算对GER进行了半定量评估。60例有GER症状的患者（51例典型症状，9例非典型症状）接受了这三项检查。还对17名正常志愿者和该系列中的12例患者在进行胃底折叠术后进行了GES检查。GES对GER的诊断特异性为1.0。在GER中，GES阳性的频率低于pH反流试验（分别为68.6%和80.4%），但差异不显著。这两项检查比测压更敏感。患者的反流指数高于对照组（p<0.0005），胃底折叠术后恢复到正常水平。观察到反流指数与pH反流试验阶段之间存在相关性。建议GES可作为TRA的替代方法用于GER的初步评估，并在手术治疗患者的随访期间重复进行。
