Styles C B, Holt S, Bowes K L, Jewell L, Hooper H R
J Can Assoc Radiol. 1984 Jun;35(2):124-7.
A method for combining scintigraphic studies of esophageal transit and gastroesophageal (GE) reflux is presented. Thirty-two patients with symptoms of GE reflux were studied. The severity of their symptoms was compared to nuclear medicine studies and esophageal mucosal biopsy. Fifteen healthy volunteers were studied as a control group for scintigraphy. The sensitivity of reflux scintigraphy to detect GE reflux as determined by esophageal histology was 70% and its specificity 87%. No relationship was observed between the magnitude of symptoms and the volume of GE reflux. A higher incidence of esophageal transit abnormalities was observed in those patients with histologic features of GE reflux than in those with normal histology. The combination of esophageal reflux and transit scintigraphy provides a way of studying some of the esophageal motor abnormalities associated with GE reflux. For clinical purposes GE reflux scintigraphy seems unsuitable as a single screening test.
本文介绍了一种结合食管通过闪烁显像研究和胃食管（GE）反流的方法。对32例有GE反流症状的患者进行了研究。将他们症状的严重程度与核医学研究及食管黏膜活检结果进行了比较。15名健康志愿者作为闪烁显像的对照组进行了研究。通过食管组织学确定，反流闪烁显像检测GE反流的敏感性为70%，特异性为87%。未观察到症状严重程度与GE反流体积之间的关系。与组织学正常的患者相比，具有GE反流组织学特征的患者中食管通过异常的发生率更高。食管反流和通过闪烁显像相结合，为研究一些与GE反流相关的食管运动异常提供了一种方法。就临床目的而言，GE反流闪烁显像似乎不适合作为单一的筛查试验。
