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一例由登革热继发的单侧动眼神经麻痹的独特病例。

A Unique Case of Unilateral Oculomotor Nerve Palsy Secondary to Dengue Fever.

作者信息

Loh Sue Anne, Wan Abdul Rahman Wan Mohd Hafidz, Sonny Teo Khairy Shamel, Abu Norlelawati

机构信息

Department of Ophthalmology and Visual Science, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, MYS.

Department of Ophthalmology, Hospital Tuanku Ja'afar, Seremban, MYS.

出版信息

Cureus. 2023 Feb 21;15(2):e35281. doi: 10.7759/cureus.35281. eCollection 2023 Feb.

Abstract

A wide range of ocular complications may arise from the mosquito-borne illness, dengue fever. We report a case of isolated unilateral oculomotor nerve palsy due to complications of dengue fever. A 50-year-old male with serologically confirmed dengue fever presented with a sudden onset of double vision with left eyelid drooping and left eye outward deviation on his day 8 of illness. Ocular examination revealed binocular diplopia with complete left eye ptosis and restriction of all left eye movements except for abduction. His left eye pupil was 8 mm dilated with a negative relative afferent pupillary defect (RAPD). A clinical diagnosis of left eye oculomotor nerve palsy with pupil involvement was established. Urgent contrasted brain imaging tests were performed and revealed to be normal. He was managed conservatively and had complete resolution of symptoms with good vision recovery within 3.5 months. Cranial mononeuropathy may be one of the various complications following dengue fever, as demonstrated in this case report. As it is an uncommon presentation, there is a need to exclude other acute causes of cranial nerve palsy. Visual prognosis is still favorable with judicious monitoring and without any treatment of steroids or immunoglobulin.

摘要

由蚊媒疾病登革热可能引发多种眼部并发症。我们报告一例因登革热并发症导致的孤立性单侧动眼神经麻痹病例。一名50岁男性,血清学确诊为登革热,在患病第8天突然出现复视,伴有左眼睑下垂和左眼向外偏斜。眼部检查发现双眼复视,左眼完全上睑下垂,除外展外左眼所有运动均受限。其左眼瞳孔散大至8 mm,相对传入性瞳孔障碍(RAPD)阴性。确立了左眼动眼神经麻痹伴瞳孔受累的临床诊断。紧急进行了脑部增强成像检查,结果显示正常。对其进行了保守治疗,症状在3.5个月内完全缓解,视力恢复良好。如本病例报告所示,颅单神经病可能是登革热后的多种并发症之一。由于这是一种不常见的表现,有必要排除其他导致颅神经麻痹的急性病因。通过审慎监测,无需使用类固醇或免疫球蛋白进行任何治疗,视觉预后仍然良好。

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