十大银屑病、特应性皮炎和化脓性汗腺炎研究重点：加拿大皮肤优先设置倡议。

Top Ten Research Priorities for Psoriasis, Atopic Dermatitis and Hidradenitis Suppurativa: The SkIN Canada Priority Setting Initiative.

机构信息

12366 Division of Dermatology, Department of Medicine, University of Toronto, Ontario, Canada.

574481 Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada.

出版信息

J Cutan Med Surg. 2023 Mar-Apr;27(2):133-139. doi: 10.1177/12034754231156103. Epub 2023 Feb 21.

DOI:10.1177/12034754231156103

PMID:36995350

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10068398/

Abstract

BACKGROUND

The Skin Investigation Network of Canada (SkIN Canada) is a new national skin research network. To shape the research landscape and ensure its value to patient care, research priorities that are important to patients, caregivers, and health care providers must be identified.

OBJECTIVES

To identify the Top Ten research priorities for 9 key skin conditions.

METHODS

We first surveyed health care providers and researchers to select the top skin conditions for future research within the categories of inflammatory skin disease, skin cancers (other than melanoma), and wound healing. For those selected skin conditions, we conducted scoping reviews to identify previous priority setting exercises. We combined the results of those scoping reviews with a survey of patients, health care providers, and researchers to generate lists of knowledge gaps for each condition. We then surveyed patients and health care providers to create preliminary rankings to prioritize those knowledge gaps. Finally, we conducted workshops of patients and health care providers to create the final Top Ten lists of research priorities for each condition.

RESULTS

Overall, 538 patients, health care providers, and researchers participated in at least one survey or workshop. Psoriasis, atopic dermatitis and hidradenitis suppurativa (inflammatory skin disease); chronic wounds, burns and scars (wound healing); and basal cell, squamous cell and Merkel cell carcinoma (skin cancer) were selected as priority skin conditions. Top Ten lists of knowledge gaps for inflammatory skin conditions encompassed a range of issues relevant to patient care, including questions on pathogenesis, prevention, non-pharmacologic and pharmacologic management.

CONCLUSIONS

Research priorities derived from patients and health care providers should be used to guide multidisciplinary research networks, funders, and policymakers in Canada and internationally.

摘要

背景

加拿大皮肤研究网络（SkIN Canada）是一个新的国家皮肤研究网络。为了塑造研究格局并确保其对患者护理的价值，必须确定对患者、护理人员和医疗保健提供者重要的研究重点。

目的

确定 9 种主要皮肤疾病的前 10 项研究重点。

方法

我们首先调查医疗保健提供者和研究人员，以确定在炎症性皮肤病、皮肤癌（除黑色素瘤外）和伤口愈合这几大类别中，未来有哪些皮肤疾病需要进一步研究。对于那些选定的皮肤疾病，我们进行了范围综述，以确定以前的重点制定工作。我们将这些范围综述的结果与患者、医疗保健提供者和研究人员的调查相结合，为每种疾病列出知识空白。然后，我们对患者和医疗保健提供者进行调查，以初步确定这些知识空白的优先顺序。最后，我们举办了患者和医疗保健提供者的研讨会，为每种疾病制定最终的前 10 项研究重点清单。

结果

共有 538 名患者、医疗保健提供者和研究人员至少参加了一次调查或研讨会。银屑病、特应性皮炎和化脓性汗腺炎（炎症性皮肤病）；慢性伤口、烧伤和疤痕（伤口愈合）；基底细胞癌、鳞状细胞癌和 Merkel 细胞癌（皮肤癌）被选为优先研究的皮肤疾病。炎症性皮肤疾病的前 10 项知识空白列表涵盖了与患者护理相关的一系列问题，包括发病机制、预防、非药物和药物管理方面的问题。