Khanna Archna, Handa Shristi, Rana Samriti, Suttee Ashish, Puri Sanjeev, Chatterjee Mary
Biotechnology Engineering, University Institute of Engineering and Technology, Panjab University, Sector 25, South Campus, Chandigarh, 160014, India.
Department of Pharmacognosy, School of Pharmaceutical Sciences, Lovely Professional University, Punjab, India.
Arch Microbiol. 2023 Mar 30;205(4):149. doi: 10.1007/s00203-023-03495-y.
Biosurfactants are surface-active molecules that are synthesized by many microorganisms like fungi, bacteria, and yeast. These molecules are amphiphilic in nature, possessing emulsifying ability, detergency, foaming, and surface-activity like characteristics. Yeast species belongs to the genus Candida has gained globally enormous interest because of the diverse properties of biosurfactants produced by theme. In contrast to synthetic surfactants, biosurfactants are claimed to be biodegradable and non-toxic which labels them as a potent industrial compound. Biosurfactants produced by this genus are reported to possess certain biological activities, such as anticancer and antiviral activities. They also have potential industrial applications in bioremediation, oil recovery, agricultural, pharmaceutical, biomedical, food, and cosmetic industries. Various species of Candida have been recognized as biosurfactant producers, including Candida petrophilum, Candida bogoriensis, Candida antarctica, Candida lipolytica, Candida albicans, Candida batistae, Candida albicans, Candida sphaerica, etc. These species produce various forms of biosurfactants, such as glycolipids, lipopeptides, fatty acids, and polymeric biosurfactants, which are distinct according to their molecular weights. Herein, we provide a detailed overview of various types of biosurfactants produced by Candida sp., process optimization for better production, and the latest updates on the applications of these biosurfactants.
生物表面活性剂是由许多微生物如真菌、细菌和酵母合成的表面活性分子。这些分子本质上是两亲性的,具有乳化能力、去污力、发泡性和表面活性等特性。由于念珠菌属产生的生物表面活性剂具有多种特性,该属酵母菌在全球范围内引起了极大的关注。与合成表面活性剂相比,生物表面活性剂据称是可生物降解且无毒的,这使其成为一种有潜力的工业化合物。据报道,该属产生的生物表面活性剂具有某些生物活性,如抗癌和抗病毒活性。它们在生物修复、石油开采、农业、制药、生物医学、食品和化妆品工业中也具有潜在的工业应用。已确认多种念珠菌为生物表面活性剂生产者,包括嗜油念珠菌、博戈里亚念珠菌、南极念珠菌、解脂念珠菌、白色念珠菌、巴蒂斯塔念珠菌、球形念珠菌等。这些菌种产生各种形式的生物表面活性剂,如糖脂、脂肽、脂肪酸和聚合生物表面活性剂,它们根据分子量不同而有所区别。在此,我们详细概述了念珠菌属产生的各类生物表面活性剂、提高产量的工艺优化以及这些生物表面活性剂应用的最新进展。