Gill R C, Cote K R, Bowes K L, Kingma Y J
Gut. 1986 Mar;27(3):293-9. doi: 10.1136/gut.27.3.293.
Extracellular electrical and contractile activities were recorded in vitro from strips of human colonic smooth muscle obtained at the time of surgery. Serosal electrical activity of longitudinally oriented strips from the taenia and intertaenial region was characterised by continuous oscillation at a frequency of 28 +/- 1/min. Contractions were marked electrically by a series of oscillations upon which spikes were superimposed. The electrical activity recorded from the submucosal surface of circularly oriented strips exhibited oscillations at 24 +/- 4/min, a frequency significantly lower (p less than 0.001) than that recorded from the serosal surface of similar preparations. The contractile force and frequency was dependent upon the part of the colon from which the strip originated; the most powerful contractions were recorded from strips of sigmoid colon. The contractile frequency of circularly oriented strips from the right colon was 6.3 +/- 0.6/min, significantly higher (p less than 0.001) than that of strips from the left colon (3.4 +/- 0.3/min). Stretching these strips caused an increase in contractile frequency to that of the electrical oscillation.
在手术过程中获取的人结肠平滑肌条带进行体外记录细胞外电活动和收缩活动。来自结肠带和结肠带间区域的纵向条带的浆膜电活动的特征是频率为28±1次/分钟的连续振荡。收缩通过一系列振荡在电活动上标记，这些振荡上叠加有尖峰。从环形条带的黏膜下表面记录的电活动表现出24±4次/分钟的振荡，该频率显著低于（p<0.001）从类似制剂的浆膜表面记录的频率。收缩力和频率取决于条带所源自的结肠部位；从乙状结肠条带记录到最强的收缩。来自右结肠的环形条带的收缩频率为6.3±0.6次/分钟，显著高于（p<0.001）来自左结肠的条带（3.4±0.3次/分钟）。拉伸这些条带会使收缩频率增加到电振荡的频率。
