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改善生态系统和野生动物健康评估:微生物组作为早期指标。

Improving the assessment of ecosystem and wildlife health: microbiome as an early indicator.

机构信息

Wildlife Conservation Medicine Research Group (WildCoM), Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193 Bellaterra, Catalonia, Spain.

Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, 08193 Bellaterra, Catalonia, Spain.

出版信息

Curr Opin Biotechnol. 2023 Jun;81:102923. doi: 10.1016/j.copbio.2023.102923. Epub 2023 Mar 28.

Abstract

Human activities are causing dramatic declines in ecosystem health, compromising the functioning of the life-support system, economic activity, and animal and human health. In this context, monitoring the health of ecosystems and wildlife populations is crucial for determining ecological dynamics and assessing management interventions. A growing body of evidence indicates that microbiome provides a meaningful early indicator of ecosystem and wildlife health. Microbiome is ubiquitous and both environmental and host-associated microbiomes rapidly reflect anthropogenic disturbances. However, we still need to overcome current limitations such as nucleic acid degradation, sequencing depth, and the establishment of baseline data to maximize the potential of microbiome studies.

摘要

人类活动正在导致生态系统健康急剧下降,危及生命支持系统的功能、经济活动以及动物和人类健康。在这种情况下,监测生态系统和野生动物种群的健康状况对于确定生态动态和评估管理干预措施至关重要。越来越多的证据表明,微生物组为生态系统和野生动物健康提供了有意义的早期指标。微生物组无处不在,环境和宿主相关的微生物组都能迅速反映人为干扰。然而,我们仍然需要克服当前的限制,如核酸降解、测序深度和基准数据的建立,以最大限度地发挥微生物组研究的潜力。

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