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探讨与葡萄糖调节受损相关的风险因素:利用动量方程评估风险因素对社区居民的影响。

Investigation of risk factors associated with impaired glucose regulation: Using the momentum equation to assess the impact of risk factors on community residents.

机构信息

Department of Traditional Chinese Medicine, Jinan Central Hospital, Jinan, Shandong, China.

Department of Ophthalmology, Jinan Central Hospital, Jinan, Shandong, China.

出版信息

Front Endocrinol (Lausanne). 2023 Mar 14;14:1145847. doi: 10.3389/fendo.2023.1145847. eCollection 2023.

DOI:10.3389/fendo.2023.1145847
PMID:36998481
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10043464/
Abstract

OBJECTIVE

To identify risk factors for impaired glucose regulation (IGR) and assess their impact on community residents, this study used a questionnaire to conduct cross-sectional surveys and analysis.

METHODS

Overall, 774 residents of an urban community in northern China (Jian city) participated in this study. Trained investigators conducted surveys using questionnaires. Based on their medical history, respondents were divided into three glucose status groups as follows: normal (NGT), IGR, and diabetes mellitus (DM). Statistical analysis of survey data was performed using SPSS v. 22.0.

RESULTS

Age, hypertension, family history of diabetes (FHD), dyslipidemia, obesity, and cardiovascular and cerebral disease (CVD) were positively correlated with IGR in men and women. IGR was negatively correlated with a sedentary lifestyle in men and positively correlated with being overweight in women. The number of type 2 diabetes mellitus (T2D) risk factors per subject was positively correlated with age in the NGT group. Glucose status deteriorated with increasing age and the number of risk factors. FHD was the strongest risk factor in both men and women.

CONCLUSIONS

Prevention of IGR includes weight control, physical activity, and prevention of hypertension and dyslipidemia, especially in subjects with FHD.

摘要

目的

本研究采用问卷调查进行横断面调查分析,旨在确定糖耐量受损(IGR)的危险因素,并评估其对社区居民的影响。

方法

本研究共纳入中国北方城市(简城)社区的 774 名居民。经过培训的调查员使用问卷进行调查。根据其病史,将受访者分为三组血糖状态:正常(NGT)、IGR 和糖尿病(DM)。使用 SPSS v. 22.0 对调查数据进行统计分析。

结果

在男性和女性中,年龄、高血压、糖尿病家族史(FHD)、血脂异常、肥胖和心脑血管疾病(CVD)与 IGR 呈正相关。IGR 与男性的久坐生活方式呈负相关,与女性的超重呈正相关。NGT 组中每位受试者的 2 型糖尿病(T2D)危险因素数量与年龄呈正相关。随着年龄和危险因素数量的增加,血糖状态恶化。FHD 是男性和女性中最强的危险因素。

结论

IGR 的预防包括控制体重、进行体育锻炼以及预防高血压和血脂异常,尤其是对于有 FHD 的人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e965/10043464/c4af0e1be123/fendo-14-1145847-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e965/10043464/c4af0e1be123/fendo-14-1145847-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e965/10043464/c4af0e1be123/fendo-14-1145847-g001.jpg

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