Sedgwick Matthew J, Saunders Christopher, Bateman Neil
Global Clinical and Medical Affairs Smith+Nephew Hull UK.
Paediatric Otolaryngology Department, Manchester Academic Health Science Centre, Royal Manchester Children's Hospital Manchester University Hospitals NHS Foundation Trust Manchester UK.
OTO Open. 2023 Feb 17;7(1):e22. doi: 10.1002/oto2.22. eCollection 2023 Jan-Mar.
To determine whether intracapsular tonsillectomy, using plasma ablation, results in differences in postoperative patient outcomes to total tonsillectomy.
A systematic review of two databases (Embase and PubMed) was conducted in March 2022 to identify published English-language randomized controlled trials and observational studies which provided a comparison between intracapsular tonsillectomy, using plasma ablation, and total tonsillectomy.
Qualitative synthesis and meta-analysis were used to compare outcomes between techniques.
Seventeen studies were identified for inclusion. Across these, 1996 and 4565 patients underwent intracapsular and total tonsillectomy, respectively. Studies included 8 randomized controlled trials, 1 prospective cohort study, and 8 retrospective cohort studies. Time to pain free, time on analgesia, time to normal diet, and time to normal activity were significantly shorter with intracapsular tonsillectomy by on average 4.2 (95% confidence interval [CI] 1.5-5.9; < .0001), 4.1 (95% CI 2.7-5.4; < .0001), 3.5 (95% CI 1.7-5.4; = .0002) and 2.8 (95% CI 1.6-4; < .0001) days, respectively. Risk of posttonsillectomy hemorrhage was significantly lower following intracapsular tonsillectomy (relative risk [RR] 0.36; 95% CI 0.16-0.81; = .0131); risk of posttonsillectomy hemorrhage requiring surgical management was lower but failed to reach significance (RR 0.52; 95% CI 0.19-1.39; = .19).
Intracapsular tonsillectomy using plasma ablation has similar efficacy in managing indications for tonsil surgery to total tonsillectomy while significantly reducing the postoperative morbidity and likelihood of posttonsillectomy hemorrhage experienced by patients, allowing them to return to their normal life faster.
确定采用等离子消融术的囊内扁桃体切除术在术后患者预后方面是否与全扁桃体切除术存在差异。
2022年3月对两个数据库(Embase和PubMed)进行了系统评价,以识别已发表的英文随机对照试验和观察性研究,这些研究对采用等离子消融术的囊内扁桃体切除术和全扁桃体切除术进行了比较。
采用定性综合分析和荟萃分析来比较不同技术之间的预后。
共纳入17项研究。其中,分别有1996例和4565例患者接受了囊内扁桃体切除术和全扁桃体切除术。研究包括8项随机对照试验、1项前瞻性队列研究和8项回顾性队列研究。囊内扁桃体切除术后无痛时间、使用镇痛药时间、恢复正常饮食时间和恢复正常活动时间显著缩短,平均分别缩短4.2天(95%置信区间[CI] 1.5 - 5.9;P < 0.0001)、4.1天(95% CI 2.7 - 5.4;P < 0.0001)、3.5天(95% CI 1.7 - 5.4;P = 0.0002)和2.8天(95% CI 1.6 - 4;P < 0.0001)。囊内扁桃体切除术后扁桃体切除术后出血的风险显著降低(相对风险[RR] 0.36;95% CI 0.16 - 0.81;P = 0.0131);需要手术处理的扁桃体切除术后出血风险较低,但未达到显著差异(RR 0.52;95% CI 0.19 - 1.39;P = 0.19)。
采用等离子消融术的囊内扁桃体切除术在治疗扁桃体手术适应证方面与全扁桃体切除术具有相似的疗效,同时显著降低了患者术后的发病率和扁桃体切除术后出血的可能性,使他们能够更快地恢复正常生活。