Department of Family Medicine, School of Medicine with Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
'Sanprom' Family Doctors' Practice, Zabrze, Poland.
Ann Agric Environ Med. 2023 Mar 31;30(1):183-189. doi: 10.26444/aaem/158024. Epub 2023 Jan 26.
Caring for people with diabetes is a challenge for doctors. GPs should be diagnostically vigilant and pay attention even to unusual symptoms reported by the patient, as they can progress quickly, impeding effective treatment. Targeted treatment of the bacteriological infection improves the prognosis in this group of patients. Its condition is to perform bacteriological tests. Statistics show that the infectious flora differ between people with diabetes and the general population.
The aim of the study was to evaluate in a group of patients with type 2 diabetes without symptoms of active infection, the following: 1) composition of microflora in the nasal cavity and throat, with particular emphasis on the frequency and type of opportunistic and pathogenic microorganisms; 2) carrier status of Staphylococcus aureus bacteria in the nose, and its relationship to diabetes control/ other comorbidities predisposing to immuno-suppression.
The study included 88 patients diagnosed with type 2 diabetes who were interviewed in the form of a questionnaire. Patients with additional systemic diseases and taking antibiotics within the last 6 weeks were excluded from the study. Microbiological tests required the collection of nasal and throat swabs from all enrolled patients.
The bacteriological analysis included 176 nasal and throat swabs taken from 88 patients with type 2 diabetes. A total of 627 species of microorganisms were identified, and 90 potentially pathogenic strains present in the nasal cavity and throat of the subjects were isolated and identified.
People with type 2 diabetes who do not show symptoms of infection are often carriers of potentially pathogenic bacteria in the nasopharynx.
照顾糖尿病患者对医生来说是一个挑战。全科医生应该具有诊断警觉性,并关注患者报告的任何不寻常症状,因为这些症状可能会迅速进展,从而阻碍有效治疗。针对细菌感染的靶向治疗可以改善这群患者的预后。其条件是进行细菌学检查。统计数据表明,糖尿病患者与普通人群的感染菌群不同。
本研究的目的是评估一组无活动性感染症状的 2 型糖尿病患者:1)鼻腔和咽喉部微生物群的组成,特别强调机会性和致病性微生物的频率和类型;2)鼻腔金黄色葡萄球菌的携带状态及其与糖尿病控制/其他易导致免疫抑制的合并症的关系。
本研究纳入了 88 名被诊断为 2 型糖尿病的患者,他们接受了问卷调查。患有其他系统性疾病和在过去 6 周内服用抗生素的患者被排除在研究之外。微生物学测试需要从所有入组患者中采集鼻腔和咽喉拭子。
共进行了 88 名 2 型糖尿病患者的 176 份鼻腔和咽喉拭子的细菌学分析。共鉴定出 627 种微生物,从研究对象的鼻腔和咽喉部位分离并鉴定出 90 种潜在的致病性菌株。
无感染症状的 2 型糖尿病患者通常是鼻咽部潜在致病细菌的携带者。