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健康人群的心率变异性统计分析:性别和身体姿势的影响。

Statistical heart rate variability analysis for healthy person: Influence of gender and body posture.

机构信息

National Institute of Technology Durgapur, Durgapur 713209, India.

National Institute of Technology Durgapur, Durgapur 713209, India; Faculty of Technology, Uttar Banga Krishi Viswavidyalaya, Coochbehar 736165, India.

出版信息

J Electrocardiol. 2023 Jul-Aug;79:81-88. doi: 10.1016/j.jelectrocard.2023.03.011. Epub 2023 Mar 26.

DOI:10.1016/j.jelectrocard.2023.03.011
PMID:37003104
Abstract

Short-term ECG-derived heart rate variability can assess autonomic function non-invasively. The purpose of this study is to investigate the influence of body posture and gender on parasympathetic-sympathetic balance by utilising electrocardiogram (ECG). A total of sixty participants including thirty males (95% CI: 23.34-26.32 years old) and thirty females (95% CI: 23.33-26.07 years old) voluntarily executed three sets of 5-min ECG recordings in supine, sitting and standing posture. A nonparametric Friedman test followed by Bonferroni post-hoc test was carried out to find the statistical differences between the group. A significant difference was observed for RR mean, low frequency (LF), high frequency (HF), ratio LF/HF and the ratio long term variability to short term variability (SD2/SD1) for p < 0.01 while respiration rate (Resp Rate), standard deviation of heart rate (STD_HR), long term variability (SD2), approximate entropy (ApEn), correlation dimension (CD) are non-significant (p > 0.01) for supine, sitting and standing. HRV indices such as standard deviation of NN (SDNN), HRV triangular index (HRVi), and triangular interpolation of NN interval (TINN) are statistically not significant for males but there are significant differences for females at a significance level 1%. Relative reliability and relatedness were evaluated through the interclass coefficient (ICC) and spearman correlation coefficient. The experimental results advocate that there is a posture-specific difference in HRV indices while the correlational studies suggest no such significant differences.

摘要

短期心电图心率变异性可无创评估自主神经功能。本研究旨在利用心电图(ECG)研究体位和性别对副交感神经-交感神经平衡的影响。共有 60 名参与者,包括 30 名男性(95%置信区间:23.34-26.32 岁)和 30 名女性(95%置信区间:23.33-26.07 岁)自愿进行了 3 组 5 分钟的仰卧位、坐位和站立位心电图记录。采用非参数 Friedman 检验和 Bonferroni 事后检验来比较组间的统计学差异。RR 均值、低频(LF)、高频(HF)、LF/HF 比值和短期变异性与长期变异性的比值(SD2/SD1)有显著差异(p<0.01),而呼吸率(Resp Rate)、心率标准差(STD_HR)、长期变异性(SD2)、近似熵(ApEn)、关联维数(CD)在仰卧位、坐位和站立位时均无显著差异(p>0.01)。HRV 指数如 NN 标准差(SDNN)、HRV 三角指数(HRVi)和 NN 间期三角插值(TINN)在男性中无统计学意义,但在女性中差异显著(p<0.01)。通过组内相关系数(ICC)和斯皮尔曼相关系数评估相对可靠性和相关性。实验结果表明 HRV 指数存在体位特异性差异,而相关研究则表明无显著差异。

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