UCLA Integrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, 11075 Santa Monica Blvd., Suite 200, Los Angeles, CA 90025, USA.
Addict Behav. 2013 Nov;38(11):2653-60. doi: 10.1016/j.addbeh.2013.06.024. Epub 2013 Jul 3.
This study investigated whether and how trajectories of substance use in adolescence were associated with obesity trajectories in young adulthood. We hypothesized that: (1) exposure to persistent substance use throughout adolescence may heighten obesity risk in young adulthood; and (2) such associations may differ once gender, ethnicity, socioeconomic status, and obesity status in adolescence, are considered.
The study included 5141 adolescents from the child sample of the 1979 National Longitudinal Survey of Youth and utilized biennial data across the 12 assessments (1986-2008) to examine trajectories of substance use behaviors (i.e., cigarette smoking, alcohol use, and marijuana use) from ages 12 to 18 and obesity trajectories from ages 20 to 24. Group-based dual trajectory modeling was applied to examine sequential associations of trajectories of each type of substance use behavior with obesity trajectories.
Three distinctive trajectory patterns were respectively identified for cigarette smoking, alcohol use, and marijuana use from ages 12 to 18, as well as for obesity status (BMI ≥ 30) from ages 20 to 24. Taking into account gender, ethnicity, socioeconomic status, and obesity status in adolescence, adolescents with the most problematic smoking trajectory (High-decreasing) were more likely to exhibit a High-obesity trajectory from ages 20 to 24. Also, adolescents with an Increasing marijuana use trajectory were more likely to exhibit an Increased obesity trajectory in young adulthood.
The current study demonstrates that adolescent substance use is associated with subsequent obesity in young adulthood. The associations appear to differ based on the type of substance use and patterns of use.
本研究旨在探讨青少年时期物质使用轨迹与成年早期肥胖轨迹之间是否存在关联，以及存在何种关联。我们假设：（1）青春期持续暴露于物质使用可能会增加成年早期肥胖的风险；（2）一旦考虑到青春期的性别、种族、社会经济地位和肥胖状况，这些关联可能会有所不同。
本研究纳入了来自 1979 年全国青年纵向调查儿童样本的 5141 名青少年，并利用 12 次评估（1986-2008 年）的两年期数据，从 12 岁到 18 岁期间，研究物质使用行为（即吸烟、饮酒和使用大麻）轨迹，以及从 20 岁到 24 岁期间肥胖轨迹。采用基于群组的双重轨迹建模来检验每种物质使用行为轨迹与肥胖轨迹的顺序关联。
从 12 岁到 18 岁期间，分别确定了吸烟、饮酒和使用大麻的三种不同轨迹模式，以及从 20 岁到 24 岁期间的肥胖状况（BMI≥30）。考虑到青春期的性别、种族、社会经济地位和肥胖状况，具有最严重吸烟轨迹（高-下降）的青少年更有可能在 20 岁到 24 岁期间表现出高肥胖轨迹。此外，具有增加大麻使用轨迹的青少年更有可能在成年早期表现出肥胖增加轨迹。
本研究表明，青少年时期的物质使用与成年早期的肥胖有关。这些关联似乎因物质使用的类型和使用模式而异。
