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分娩活跃期诊断时的宫颈扩张程度决定了分娩方式和围产期结局:马来西亚单一三级中心的回顾性研究。

Cervical dilatation at diagnosis of active phase of labour determines the mode of delivery and peripartum outcomes: a retrospective study in a single tertiary centre in Malaysia.

机构信息

Department of Obstetrics & Gynaecology, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, 56000, Malaysia.

Department of Obstetrics & Gynaecology, Hospital Canselor Tuanku Muhriz, Jalan Yaacob Latif, Bandar Tun Razak, Kuala Lumpur, 56000, Malaysia.

出版信息

BMC Pregnancy Childbirth. 2023 Apr 1;23(1):221. doi: 10.1186/s12884-023-05523-7.

Abstract

BACKGROUND

There is an increasing trend of Caesarean section rate in Malaysia. Limited evidence demonstrated the benefits of changing the demarcation of the active phase of labour.

METHODS

This was a retrospective study of 3980 singletons, term pregnancy, spontaneous labouring women between 2015 and 2019 comparing outcomes between those with cervical dilation of 4 versus 6 cm at diagnosis of the active phase of labour.

RESULTS

A total of 3403 (85.5%) women had cervical dilatation of 4 cm, and 577 (14.5%) at 6 cm upon diagnosis of the active phase of labour. Women in 4 cm group were significantly heavier at delivery (p = 0.015) but significantly more multiparous women were in 6 cm group (p < 0.001). There were significantly fewer women in the 6 cm group who needed oxytocin infusion (p < 0.001) and epidural analgesia (p < 0.001) with significantly lower caesarean section rate (p < 0.001) done for fetal distress and poor progress (p < 0.001 both). The mean duration from diagnosis of the active phase of labour until delivery was significantly shorter in the 6 cm group (p < 0.001) with lighter mean birth weight (p = 0.019) and fewer neonates with arterial cord pH < 7.20 (p = 0.047) requiring neonatal intensive care unit admissions (p = 0.01). Multiparity (AOR = 0.488, p < 0.001), oxytocin augmentation (AOR = 0.487, p < 0.001) and active phase of labour diagnosed at 6 cm (AOR = 0.337, p < 0.001) reduced the risk of caesarean delivery. Caesarean delivery increased the risk of neonatal intensive care admission by 27% (AOR = 1.73, p < 0.001).

CONCLUSIONS

Active phase of labour at 6 cm cervical dilatation is associated with reduced primary caesarean delivery rate, labour intervention, shorter labour duration and fewer neonatal complications.

摘要

背景

马来西亚的剖宫产率呈上升趋势。有限的证据表明改变活跃期的界定是有益的。

方法

这是一项回顾性研究,纳入了 2015 年至 2019 年间 3980 名单胎足月、自发性分娩的妇女,比较了活跃期宫颈扩张 4cm 和 6cm 时的结局。

结果

共有 3403 名(85.5%)妇女在诊断活跃期时宫颈扩张 4cm,577 名(14.5%)妇女在诊断活跃期时宫颈扩张 6cm。4cm 组的产妇分娩时体重明显更重(p=0.015),但 6cm 组的多产妇明显更多(p<0.001)。6cm 组需要催产素输注(p<0.001)和硬膜外镇痛(p<0.001)的妇女明显较少,因胎儿窘迫和进展不良而进行剖宫产的比例明显较低(p<0.001 均)。从诊断活跃期到分娩的平均时间在 6cm 组明显缩短(p<0.001),平均出生体重较轻(p=0.019),动脉脐带 pH<7.20 的新生儿较少(p=0.047),需要新生儿重症监护病房入院的新生儿较少(p=0.01)。多产妇(优势比[OR] = 0.488,p<0.001)、催产素增强(OR = 0.487,p<0.001)和诊断活跃期时宫颈扩张 6cm(OR = 0.337,p<0.001)降低了剖宫产的风险。剖宫产使新生儿重症监护病房入院的风险增加了 27%(OR = 1.73,p<0.001)。

结论

活跃期宫颈扩张 6cm 与降低原发性剖宫产率、减少分娩干预、缩短分娩时间和减少新生儿并发症有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/153a/10067294/9f0a6f75995f/12884_2023_5523_Fig1_HTML.jpg

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