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职业性噪声暴露的听力正常个体的中耳肌反射。

Middle Ear Muscle Reflex in Normal-Hearing Individuals with Occupational Noise Exposure.

机构信息

Facility for Advanced Auditory Research (FAAR), Department of Audiology, All India Institute of Speech and Hearing, Mysuru, Karnataka, India.

Department of Audiology, All India Institute of Speech and Hearing, Mysuru, Karnataka, India.

出版信息

Noise Health. 2023 Jan-Mar;25(116):1-7. doi: 10.4103/nah.nah_3_22.

Abstract

OBJECTIVES

Noise-induced cochlear synaptopathy is studied extensively in animal models. The diagnosis of synaptopathy in humans is challenging and the roles of many noninvasive measures in identifying synaptopathy are being explored. The acoustic middle ear muscle reflex (MEMR) can be considered as a vital tool since noise exposure affects the low-spontaneous rate fibers that play an important role in elicitation of MEMR. The present study aimed at measuring MEMR threshold and MEMR strength.

DESIGN

The study participants were divided into two groups. All the participants had normal-hearing thresholds. The control group consisted of 25 individuals with no occupational noise exposure whereas noise exposure group had 25 individuals who were exposed to occupational noise of 85 dBA for a minimum period of 1 year. MEMR threshold and strength was assessed for pure tones (500 Hz and 1000 Hz) and broadband noise.

RESULTS

The results showed that the MEMR threshold was similar in both the groups. MEMR strength was reduced in noise exposure group compared to control group.

CONCLUSIONS

The results of the study suggest that MEMR strength could be used as a sensitive measure in identifying cochlear synaptopathy with careful consideration of the stimulus characteristics.

摘要

目的

噪声诱导的耳蜗突触病在动物模型中得到了广泛研究。人类突触病的诊断具有挑战性,许多非侵入性措施在识别突触病中的作用正在探索中。中耳声肌肉反射(MEMR)可被视为一种重要的工具,因为噪声暴露会影响到低自发性纤维,而这些纤维在引发 MEMR 中起着重要作用。本研究旨在测量 MEMR 阈值和 MEMR 强度。

设计

研究参与者分为两组。所有参与者的听力阈值均正常。对照组由 25 名无职业噪声暴露的个体组成,而噪声暴露组由 25 名接触职业噪声 85 dBA 至少 1 年的个体组成。评估了纯音(500 Hz 和 1000 Hz)和宽带噪声的 MEMR 阈值和强度。

结果

结果表明,两组的 MEMR 阈值相似。与对照组相比,噪声暴露组的 MEMR 强度降低。

结论

研究结果表明,MEMR 强度可以作为一种敏感的测量方法,用于识别耳蜗突触病,但需要仔细考虑刺激特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1124/10301919/a6a67481fc8b/NH-25-1-g001.jpg

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