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2
Clinico-Epidemiological Characteristics of Hidradenitis Suppurativa: A Retrospective Cohort Study from a Tertiary Care Centre in Northern India.化脓性汗腺炎的临床流行病学特征:来自印度北部一家三级医疗中心的回顾性队列研究
Indian Dermatol Online J. 2021 Jun 20;12(4):561-565. doi: 10.4103/idoj.IDOJ_743_20. eCollection 2021 Jul-Aug.
3
Features Associated With Quality of Life Impairment in Hidradenitis Suppurativa Patients.化脓性汗腺炎患者生活质量受损相关特征。
Front Med (Lausanne). 2021 Apr 27;8:676241. doi: 10.3389/fmed.2021.676241. eCollection 2021.
4
Quality-of-Life Impairment among Patients with Hidradenitis Suppurativa: A Cross-Sectional Study of 1795 Patients.化脓性汗腺炎患者的生活质量损害:一项对1795例患者的横断面研究。
Life (Basel). 2021 Jan 8;11(1):34. doi: 10.3390/life11010034.
5
The most recent advances in understanding and managing hidradenitis suppurativa.化脓性汗腺炎的理解与管理方面的最新进展。
F1000Res. 2020 Aug 26;9. doi: 10.12688/f1000research.26083.1. eCollection 2020.
6
Hidradenitis Suppurativa: Inside and Out.化脓性汗腺炎:内外剖析
Indian J Dermatol. 2018 Mar-Apr;63(2):91-98. doi: 10.4103/ijd.IJD_412_16.
7
Descriptive Epidemiology of Hidradenitis Suppurativa in Greece: A Study of 152 Cases.希腊化脓性汗腺炎的描述性流行病学:一项152例病例的研究。
Skin Appendage Disord. 2017 Oct;3(4):197-201. doi: 10.1159/000475822. Epub 2017 May 17.
8
Quality-of-life impairment in patients with hidradenitis suppurativa: a Canadian study.化脓性汗腺炎患者的生活质量损害:一项加拿大的研究。
Am J Clin Dermatol. 2015 Feb;16(1):61-5. doi: 10.1007/s40257-014-0105-5.
9
Successful treatment of severe hidradenitis suppurativa with anakinra.用阿那白滞素成功治疗重度化脓性汗腺炎。
JAMA Dermatol. 2013 Oct;149(10):1192-4. doi: 10.1001/jamadermatol.2013.5377.
10
Psychophysical aspects of hidradenitis suppurativa.化脓性汗腺炎的心理物理学方面。
Acta Derm Venereol. 2010 May;90(3):264-8. doi: 10.2340/00015555-0866.

一项评估影响化脓性汗腺炎患者皮肤病生活质量指数因素的前瞻性观察研究。

A Prospective Observational Study to Evaluate the Factors Affecting the Dermatology Life Quality Index in Patients With Hidradenitis Suppurativa.

作者信息

Menon Aastha, Gupta Pawan, Suri Ravleen K, Thakare Vaishali, Dubey Lily, Patil Sharmila

机构信息

Dermatology, Dr. D. Y. Patil Hospital, Navi Mumbai, IND.

Dermatology, Bundelkhand Medical College, Sagar, IND.

出版信息

Cureus. 2023 Feb 26;15(2):e35510. doi: 10.7759/cureus.35510. eCollection 2023 Feb.

DOI:10.7759/cureus.35510
PMID:37007422
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10050991/
Abstract

BACKGROUND

Hidradenitis suppurativa (HS) is a chronic, relapsing inflammatory skin disease that significantly affects the quality of life of patients. Multiple factors affect the disease's course and severity. HS is a debilitating disease and often recalcitrant to treatment, resulting in a deterioration of quality of life; hence, there is a need to evaluate the factors affecting the quality of life in patients with HS.

OBJECTIVES

The objective of the study was to evaluate the various demographic and disease-related factors that affect the quality of life of patients with HS.

MATERIALS AND METHODS

This is a prospectively scored questionnaire-based observational study. Data from 30 patients with HS were analyzed for the association of disease-related factors like Hurley's staging, site, duration, past history, and comorbidities with the Dermatology Life Quality Index (DLQI).

RESULTS

A statistically significant relationship was found between DLQI and Hurley staging (p=0.000). The most common sites involved were the axilla and inguinal regions. Among the sites involved, the neck (p=0.002), abdomen (p=0.002), back (p=0.002), thighs (p=0.042), and gluteal (p=0.000) regions have a statistically significant association with DLQI. Prior histories of rheumatoid arthritis, scarring, surgery, lymphadenitis, and pilonidal sinus showed a statistically significant association with DLQI.

CONCLUSION

The disease severity significantly hampers the quality of life of patients with HS. The disease site and presence of other comorbidities also influence the outcome. Our study will help healthcare providers better understand and fulfill the needs of patients suffering from HS.

摘要

背景

化脓性汗腺炎(HS)是一种慢性复发性炎症性皮肤病,严重影响患者的生活质量。多种因素影响该病的病程和严重程度。HS是一种使人衰弱的疾病,且常常对治疗具有顽固性,导致生活质量下降;因此,有必要评估影响HS患者生活质量的因素。

目的

本研究的目的是评估影响HS患者生活质量的各种人口统计学和疾病相关因素。

材料与方法

这是一项基于前瞻性评分问卷的观察性研究。分析了30例HS患者的数据,以探讨疾病相关因素如Hurley分期、发病部位、病程、既往史和合并症与皮肤病生活质量指数(DLQI)之间的关联。

结果

发现DLQI与Hurley分期之间存在统计学显著关系(p = 0.000)。最常受累的部位是腋窝和腹股沟区。在受累部位中,颈部(p = 0.002)、腹部(p = 0.002)、背部(p = 0.002)、大腿(p = 0.042)和臀部(p = 0.000)区域与DLQI存在统计学显著关联。类风湿关节炎、瘢痕形成、手术、淋巴结炎和藏毛窦的既往史与DLQI存在统计学显著关联。

结论

疾病严重程度显著妨碍HS患者的生活质量。疾病部位和其他合并症的存在也会影响结果。我们的研究将有助于医疗保健提供者更好地理解并满足HS患者的需求。