Krajewski Piotr K, Matusiak Łukasz, von Stebut Esther, Schultheis Michael, Kirschner Uwe, Nikolakis Georgios, Szepietowski Jacek C
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Department of Dermatology, Faculty of Medicine, University of Cologne, 50923 Cologne, Germany.
Life (Basel). 2021 Jan 8;11(1):34. doi: 10.3390/life11010034.
The chronic, inflammatory skin disorder hidradenitis suppurativa (HS) is associated well documented negative influences on patients' quality of life (QoL). The aim of this study was to present more robust data on patients' QoL impairment by demographic data and its correlation with well-known HS risk factors on a cohort of 1795 German patients. The instrument used for measuring QoL in this study was the Dermatology Life Quality Index (DLQI). Overall, patients reported a very large effect of HS on their QoL (mean DLQI: 13.2 ± 8.1 points), and 22% of the analyzed population even reported to consider the effect as extremely large. Women tended to experience significantly higher impairment than men ( < 0.001). QoL impairment correlated positively with pain (r = 0.581, < 0.001), HS severity (measured by the International Hidradenitis Suppurativa Severity Score System (IHS4)) as well as Hurley. Neck involvement tended to decrease QoL significantly more than any other location (14.7 ± 8.3 points). This study confirms the enormous influence of HS on patients' QoL in a large cohort. Knowledge of QoL impairment in such patients is crucial for proper understanding and holistic management of this disease.
慢性炎症性皮肤病化脓性汗腺炎（HS）对患者的生活质量（QoL）有诸多负面影响，这已得到充分记录。本研究的目的是通过人口统计学数据，呈现关于1795名德国患者队列中QoL受损情况的更有力数据，以及其与HS已知风险因素的相关性。本研究中用于测量QoL的工具是皮肤病生活质量指数（DLQI）。总体而言，患者报告HS对其QoL有非常大的影响（平均DLQI：13.2±8.1分），甚至22%的分析人群报告认为影响极大。女性往往比男性经历更显著的损害（<0.001）。QoL损害与疼痛（r = 0.581，<0.001）、HS严重程度（通过国际化脓性汗腺炎严重程度评分系统（IHS4）测量）以及赫尔利分级呈正相关。颈部受累往往比其他任何部位更显著地降低QoL（14.7±8.3分）。本研究证实了HS在一个大型队列中对患者QoL的巨大影响。了解此类患者的QoL损害对于正确理解和全面管理这种疾病至关重要。
