Chen Xi, Lai Yu
School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Front Microbiol. 2023 Mar 16;14:1099132. doi: 10.3389/fmicb.2023.1099132. eCollection 2023.
BACKGROUND: As an effective strategy that reduces transmission among people at high risk of human immunodeficiency virus (HIV), pre-exposure prophylaxis (PrEP) has revolutionized HIV prevention. Our study aims to provide a reference for the development of relevant research and the formulation of prevention and control policies for HIV. METHODS: Through CiteSpace software, this study aims to present a comprehensive overview of the HIV PrEP knowledge structure, hotspots, and frontiers. We searched the Web of Science Core Collection for studies published between 2012 and 2022 related to HIV PrEP, and 3,243 papers remained after selection. RESULTS: The number of HIV PrEP publications has increased over the past few years. A close integration and exchange of HIV PrEP research findings has taken place between countries and authors. Major ongoing research trends include long-term injection PrEP, the impact of chlamydia on HIV PrEP, and individual awareness of and attitudes toward HIV PrEP. Thus, more attention should be paid to innovations and breakthroughs in drugs, the factors that affect HIV transmission and susceptibility, and the future promotion of public acceptance of HIV PrEP. CONCLUSION: This study offers a systematic, objective, and comprehensive analysis of the related articles. It will assist scholars in understanding the dynamic evolution of HIV PrEP research and identifying future research areas to better advance the development of the field.
背景:作为一种减少人类免疫缺陷病毒(HIV)高危人群之间传播的有效策略,暴露前预防(PrEP)彻底改变了HIV预防模式。我们的研究旨在为HIV相关研究的开展及防控政策的制定提供参考。 方法:本研究旨在通过CiteSpace软件全面概述HIV PrEP的知识结构、热点及前沿。我们在科学网核心合集数据库中检索了2012年至2022年间发表的与HIV PrEP相关的研究,筛选后保留3243篇论文。 结果:过去几年中,HIV PrEP相关出版物数量有所增加。各国及作者之间在HIV PrEP研究成果方面进行了紧密的整合与交流。当前主要的研究趋势包括长效注射PrEP、衣原体对HIV PrEP的影响以及个体对HIV PrEP的认知和态度。因此,应更加关注药物创新与突破、影响HIV传播和易感性的因素以及未来提高公众对HIV PrEP的接受度。 结论:本研究对相关文章进行了系统、客观且全面的分析。它将帮助学者了解HIV PrEP研究的动态演变,并确定未来的研究领域,以更好地推动该领域的发展。
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