Bisson Courtney, Dautel Sydney, Patel Easha, Suresh Sunitha, Dauer Patricia, Rana Sarosh
Department of Obstetrics and Gynecology, NorthShore University Health System, Evanston, IL, United States.
Front Med (Lausanne). 2023 Mar 16;10:1144170. doi: 10.3389/fmed.2023.1144170. eCollection 2023.
Preeclampsia is a disease with far-reaching consequences that extend beyond the immediate postpartum period and have a significant impact later in life. Preeclampsia exerts an effect on most organ systems in the body. These sequelae are mediated in part by the incompletely elucidated pathophysiology of preeclampsia and the associated vascular changes.
Current research focuses on unraveling the pathophysiology of preeclampsia with the goal of implementing accurate screening and treatment modalities based on disease development and progression. Preeclampsia causes significant short- and long-term maternal morbidity and mortality, not only in the cardiovascular system but also in other organ systems throughout the body. This impact persists beyond pregnancy and the immediate postpartum period.
The goal of this review is to discuss the current understanding of the pathophysiology of preeclampsia as it relates to the adverse health consequences in patients impacted by this disease, along with a brief discussion of ways to improve overall outcomes.
子痫前期是一种具有深远影响的疾病，其影响不仅限于产后即刻，对日后生活也有重大影响。子痫前期会对身体的大多数器官系统产生作用。这些后遗症部分是由子痫前期尚未完全阐明的病理生理学以及相关血管变化介导的。
当前的研究致力于揭示子痫前期的病理生理学，目标是基于疾病的发展和进程实施准确的筛查和治疗方式。子痫前期会导致严重的短期和长期孕产妇发病和死亡，不仅在心血管系统，还在全身的其他器官系统。这种影响在妊娠及产后即刻之后仍会持续。
本综述的目的是讨论目前对子痫前期病理生理学的理解，因为它与受该疾病影响的患者的不良健康后果相关，同时简要讨论改善总体结局的方法。
