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涎腺内镜取石术后涎腺功能恢复的前瞻性研究。

A Prospective Study of Recovery of Salivary Gland Function After Calculus Removal by Sialendoscopy.

作者信息

Lakshmi Nair S, Faizal Bini, Hari Harsha

机构信息

Department of ENT, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeedham University, Kochi, India.

Department of Biostatistics, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeedham University, Kochi, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Mar;75(1):88-93. doi: 10.1007/s12070-023-03526-6. Epub 2023 Feb 10.

Abstract

Sialendoscopy is gaining popularity in treating obstructive sialolithiasis as a gland preserving procedure. The study aimed to determine if the salivary glands recovered apart from symptomatic improvement after interventional sialendoscopy for calculus removal. A prospective comparative study was conducted in a tertiary care center on 24 patients diagnosed with sialolithiasis. The eligibility criterion was patients who underwent calculus removal through interventional sialendoscopy. All patients underwent objective and subjective methods of assessments of function of the salivary glands with the help of salivary Technetium (Tc) 99 Scintigraphy, measurement of salivary flow rate, Chronic obstructive sialadenitis symptoms (COSS), and xerostomia index (XI) questionnaires. Assessments were done before the procedure and repeated after 3 months. Categorical variables were expressed using frequency and percentage. Numerical variables were represented using mean and standard deviation. To test the statistical significance of the difference in the mean of the four parameters Wilcoxen sign ranked test was used. According to our study improvement in functionality was noted in all of the subjective and objective parameters assessed namely Tc scintigraphy, salivary flow rate, COSS questionnaire, and XI questionnaire, with a statistically significant value (< 0.001). Functionality of salivary gland showed improvement within 3 months of calculus removal through sialendoscopy. There was a marked improvement in the symptoms after sialendoscopy. This study demonstrates that removal of obstructing calculus results in rapid recovery of glandular function thereby emphasizing the need for salivary gland preservation. : Level III.

摘要

涎腺内镜作为一种保留腺体的手术,在治疗阻塞性涎石病方面越来越受欢迎。本研究旨在确定在通过介入性涎腺内镜取石术后,涎腺功能除了症状改善外是否也得到恢复。在一家三级医疗中心对24例诊断为涎石病的患者进行了一项前瞻性对照研究。入选标准为通过介入性涎腺内镜取石的患者。所有患者借助唾液锝(Tc)99闪烁扫描、唾液流速测量、慢性阻塞性涎腺炎症状(COSS)问卷和口干指数(XI)问卷,接受了涎腺功能的客观和主观评估方法。在手术前进行评估,并在3个月后重复评估。分类变量用频率和百分比表示。数值变量用均值和标准差表示。为检验四个参数均值差异的统计学显著性,使用了Wilcoxon符号秩和检验。根据我们的研究,在所有评估的主观和客观参数,即Tc闪烁扫描、唾液流速、COSS问卷和XI问卷中,均观察到功能改善,具有统计学显著性(<0.001)。通过涎腺内镜取石后,涎腺功能在3个月内有所改善。涎腺内镜检查后症状有明显改善。本研究表明,去除阻塞性结石可使腺体功能迅速恢复,从而强调了保留涎腺的必要性。:三级。

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