Hyassat Dana, Abu Noor Nancy, AlAjlouni Qais, Jarrar Yazan, Qarajeh Raed, Mahasneh Awn, Elzoubi Zaid, Khader Yousef, Farahid Oraib, El-Khateeb Mohammed, Ajlouni Kamel
The National Center for Diabetes, Endocrinology and Genetics, University of Jordan Amman, Amman.
Jordan University of Science and Technology (JUST), Al Ramtha, Irdid, Jordan.
Ann Med Surg (Lond). 2023 Mar 24;85(3):439-445. doi: 10.1097/MS9.0000000000000272. eCollection 2023 Mar.
To determine the level of glycemic, blood pressure (BP), and lipids control among patients with type 2 diabetes mellitus (DM) attending the National Center for Diabetes, Endocrinology and Genetics and to determine factors associated with poor control.
A cross-sectional study of 1200 Jordanian type 2 DM patients was included in this study during the period of December 2017-December 2018. We reviewed the charts of these patients until January 2020. Data obtained from medical records included information about sociodemographic variables, anthropometric measurements, glycated hemoglobin (HbA1c), BP, low-density lipoprotein (LDL), the presence of DM complications, and treatment.
The percentage of subjects who had HbA1c values of less than 7% was 41.7%. BP targets (<140/90 and 130/80 mmHg) were achieved in 61.9 and 22% of our patients, respectively. LDL targets less than 100 and 70 mg/dl or less were achieved in 52.2 and 15.9% of our studied population. Only 15.4% of our patients could have simultaneous control of HbA1c less than 7%, BP less than 140/90 mmHg, and LDL less than 100 mg/dl. Factors associated with poor glycemic control were obesity [odds ratio (OR)=1.9], DM duration between 5 and 10 years or more than 10 years (OR=1.8 and 2.5, respectively), and the use of a combination of oral hypoglycemic agent plus insulin or insulin alone (OR=2.4 and 6.2, respectively). Moreover, factors associated with uncontrolled BP (≥140/90) were male gender (OR=1.4), age 50-59 years or at least 60 years (OR=3.3 and 6.6, respectively), overweight and obesity (OR=1.6 and 1.4, respectively), insulin use (OR=1.6), and LDL at least 100 mg/dl (OR=1.4).
The overall prevalence of poor glycemic control was high and alarming. Future research should focus on capturing all variables that may impact glycemic, BP, and dyslipidemia control, with special emphasis on a healthy lifestyle that would be of great benefit in this control.
确定在国家糖尿病、内分泌与遗传学中心就诊的2型糖尿病（DM）患者的血糖、血压（BP）和血脂控制水平，并确定与控制不佳相关的因素。
本研究纳入了2017年12月至2018年12月期间1200例约旦2型DM患者的横断面研究。我们查阅了这些患者截至2020年1月的病历。从医疗记录中获得的数据包括社会人口统计学变量、人体测量学指标、糖化血红蛋白（HbA1c）、血压、低密度脂蛋白（LDL）、DM并发症的存在情况以及治疗情况。
HbA1c值低于7%的受试者百分比为41.7%。血压目标（<140/90和130/80 mmHg）分别在61.9%和22%的患者中实现。LDL目标低于100和70 mg/dl或更低分别在52.2%和15.9%的研究人群中实现。只有15.4%的患者能够同时将HbA1c控制在7%以下、血压控制在140/90 mmHg以下且LDL控制在100 mg/dl以下。与血糖控制不佳相关的因素包括肥胖[比值比（OR）=1.9]、DM病程在5至10年或超过10年（OR分别为1.8和2.5）以及使用口服降糖药加胰岛素联合治疗或仅使用胰岛素治疗（OR分别为2.4和6.2）。此外，与血压未控制（≥140/90）相关的因素包括男性（OR=1.4）、年龄50 - 59岁或至少60岁（OR分别为3.3和6.6）、超重和肥胖（OR分别为1.6和1.4）、使用胰岛素（OR=1.6）以及LDL至少100 mg/dl（OR=1.4）。
血糖控制不佳的总体患病率很高且令人担忧。未来的研究应关注捕捉所有可能影响血糖、血压和血脂异常控制的变量，特别强调健康的生活方式，这对这种控制将大有裨益。
