Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), Basrah Health Directorate, University of Basrah, Basrah, Iraq.
Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), Basrah Health Directorate, University of Basrah, Basrah, Iraq.
Diabetes Metab Syndr. 2020 May-Jun;14(3):265-272. doi: 10.1016/j.dsx.2020.03.008. Epub 2020 Mar 26.
This study was designed to assess the achievement of a glycated hemoglobin (HbA1c) target in Iraqi type 2 diabetes mellitus (T2DM) patients via retrospective analysis of a tertiary care database over a 9-year period.
A total of 12,869 patients with T2DM with mean (SEM) age: 51.4(0.1) years, and 54.4% were females registered into Faiha Specialized Diabetes, Endocrine and Metabolism Center(FDEMC) database between August 2008 and July 2017 were included in this retrospective study. Data were recorded for each patient during routine follow-up visits performed at the center every 3-12 months.
Patients were under oral antidiabetic drugs (OAD; 45.8%) or insulin+ OAD (54.2%) therapy. Hypertension was evident in 42.0% of patients, while dyslipidemia was noted in 70.5%. Glycemic control (HbA1c <7%) was achieved by 13.8% of patients. Multivariate analysis revealed <55 years of age, female gender, >3 years duration of diabetes, HbA1c >10% at the first visit, presence of dyslipidemia, and insulin treatment as significant determinants of an increased risk of poor glycemic control. BMI <25 kg/m and presence of hypertension were associated with a decreased risk of poor glycemic control.
Using data from the largest cohort of T2DM patients from Iraq to date, this tertiary care database analysis over a 9-year period indicated poor glycemic control. Younger patient age, female gender, longer disease duration, initially high HbA1c levels, dyslipidemia, insulin treatment, overweight and obesity, and lack of hypertension were associated with an increased risk of poor glycemic control in Iraqi T2DM patients.
本研究旨在通过对一家三级保健数据库中 9 年的数据进行回顾性分析,评估伊拉克 2 型糖尿病(T2DM)患者糖化血红蛋白(HbA1c)目标的达标情况。
共纳入 2008 年 8 月至 2017 年 7 月期间在 Faiha 内分泌和代谢疾病专科中心(FDEMC)登记的 12869 例 T2DM 患者,平均(SEM)年龄为 51.4(0.1)岁,女性占 54.4%。在中心每 3-12 个月进行的常规随访中记录每位患者的数据。
患者接受口服降糖药(OAD;45.8%)或胰岛素+OAD(54.2%)治疗。42.0%的患者存在高血压,70.5%的患者存在血脂异常。HbA1c<7%的患者血糖控制达标率为 13.8%。多变量分析显示,年龄<55 岁、女性、糖尿病病程>3 年、初诊时 HbA1c>10%、存在血脂异常和胰岛素治疗是血糖控制不佳的显著危险因素。BMI<25kg/m 和存在高血压与血糖控制不佳的风险降低相关。
利用来自伊拉克迄今最大的 T2DM 患者队列的数据,本项为期 9 年的三级保健数据库分析表明,血糖控制不佳。在伊拉克 T2DM 患者中,年轻的患者年龄、女性、较长的病程、初诊时较高的 HbA1c 水平、血脂异常、胰岛素治疗、超重和肥胖以及缺乏高血压与血糖控制不佳的风险增加相关。