白内障超声乳化吸除联合玻璃体切除术治疗非感染性葡萄膜炎患者的白内障
Combined Phacoemulsification and Pars Plana Vitrectomy for the Treatment of Cataract in Patients With Noninfectious Uveitis.
作者信息
Conrady Christopher D, Shakoor Akbar, Patel Rachel, Larochelle Marissa, Moshirfar Majid, Chaya Craig J, Jacoby Rachael, Vitale Albert T
机构信息
Department of Ophthalmology, John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.
Department of Ophthalmology, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA.
出版信息
J Vitreoretin Dis. 2020 Jul 1;4(5):393-400. doi: 10.1177/2474126420930489. eCollection 2020 Sep-Oct.
PURPOSE
This work evaluates the role of combined phacoemulsification and vitrectomy surgery in the management of cataract associated with noninfectious uveitis.
METHODS
A retrospective chart review was conducted of all patients aged 7 years or older who underwent a combined surgical approach from 2005 to 2018.
RESULTS
Eighty-five eyes of 67 patients were included in the study; 10.7% of eyes had a best-corrected visual acuity (BCVA) of 20/40 or better at time of surgery. At 1-year follow-up, 63.4% of eyes had a BCVA 20/40 or better and 7.6% had a BCVA of 20/200 or worse. There was an overall decrease in cystoid macular edema after surgery compared with preoperatively (47.6% vs 34.5% presurgery and postsurgery, respectively). Complete inflammatory disease remission off immunomodulatory therapy and systemic steroids was achieved in 21.1% of patients.
CONCLUSIONS
A combined surgical approach is effective in visual rehabilitation in patients with uveitic cataracts and may promote inflammatory disease remission specifically in intermediate uveitis.
目的
本研究评估白内障超声乳化吸除联合玻璃体切除术在非感染性葡萄膜炎相关性白内障治疗中的作用。
方法
对2005年至2018年期间接受联合手术治疗的所有7岁及以上患者进行回顾性病历审查。
结果
本研究纳入了67例患者的85只眼；10.7%的患眼在手术时最佳矫正视力（BCVA）为20/40或更好。在1年随访时，63.4%的患眼BCVA为20/40或更好，7.6%的患眼BCVA为20/200或更差。与术前相比，术后黄斑囊样水肿总体有所减轻（术前和术后分别为47.6%和34.5%）。21.1%的患者在停用免疫调节治疗和全身类固醇后实现了炎症性疾病的完全缓解。
结论
联合手术方法对葡萄膜炎性白内障患者的视力恢复有效，并且可能特别促进中间葡萄膜炎患者炎症性疾病的缓解。
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