Burckhard Braden A, Mathews Nathan R, Altaweel Michael M, Chang Jonathan S, Ip Michael S, Gottlieb Justin L
Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA.
Doheny Eye Center, University of California Los Angeles, Los Angeles, CA, USA.
J Vitreoretin Dis. 2021 May 6;6(2):122-125. doi: 10.1177/24741264211009505. eCollection 2022 Mar-Apr.
This work compares best-corrected visual acuity (BCVA) and central retinal thickness (CRT) outcome measures following pars plana vitrectomy (PPV) with and without internal limiting membrane (ILM) peel for epiretinal membrane (ERM).
A retrospective cohort study was conducted of 114 eyes of 114 patients with visually significant ERM undergoing PPV with membrane peel (PPV/MP) at a single institution. CRT measurements were collected from Heidelberg and Zeiss spectral-domain optical coherence tomography imaging units. Results compared preoperative and postoperative CRT and BCVA among patients with at least 60 days of follow-up.
A total of 114 eyes with ERM met the inclusion criteria. Eighty-one eyes (71%) underwent PPV/MP with ILM peel and 33 eyes (29%) underwent PPV/MP without ILM peel. There was no statistically significant difference between preoperative CRT between the 2 study groups ( = .95). The mean follow-up time of eyes undergoing PPV/MP without ILM peel and with ILM peel was 391 days and 319 days, respectively. There was no statistical difference in the mean reduction of CRT between the 2 groups ( = .470). Both groups had improvement of BCVA following surgery and there was no statistical difference in final logMAR visual acuity when comparing the 2 groups ( = .738).
There was an overall improvement of CRT and BCVA among patients undergoing PPV/MP for ERM with or without ILM peel. There was no statistically significant difference in the final BCVA or CRT between the 2 groups.
本研究比较了行或不行内界膜（ILM）剥除术的玻璃体切割术（PPV）治疗视网膜前膜（ERM）后的最佳矫正视力（BCVA）和视网膜中央厚度（CRT）的结果指标。
对在单一机构接受PPV联合膜剥除术（PPV/MP）治疗具有明显视力损害的ERM的114例患者的114只眼进行回顾性队列研究。从海德堡和蔡司光谱域光学相干断层扫描成像设备收集CRT测量数据。比较至少随访60天的患者术前和术后的CRT及BCVA。
共有114只患有ERM的眼睛符合纳入标准。81只眼（71%）接受了PPV/MP联合ILM剥除术，33只眼（29%）接受了PPV/MP但未行ILM剥除术。两个研究组术前CRT无统计学显著差异（ = 0.95）。未行ILM剥除术和行ILM剥除术的眼睛的平均随访时间分别为391天和319天。两组之间CRT的平均降低值无统计学差异（ = 0.470）。两组术后BCVA均有改善，比较两组最终的对数最小分辨角视力时无统计学差异（ = 0.738）。
接受PPV/MP治疗ERM的患者，无论是否行ILM剥除术，CRT和BCVA总体上均有改善。两组之间最终的BCVA或CRT无统计学显著差异。
